Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory Parameters
Objective:In our study, we aimed to investigate the long-term effects of the acute phase parameters of C-reactive protein, procalcitonin, D-dimer, lymphocyte, thrombocyte and ferritin on the respiratory function parameters in patients hospitalized due to Coronavirus disease-2019 (COVID-19) pneumonia...
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| Format: | Article |
| Language: | English |
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Galenos Yayinevi
2023-09-01
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| Series: | Bagcilar Medical Bulletin |
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| Online Access: |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/tips-for-6-months-after-covd-19-pneumonia-acute-nf/60754
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| _version_ | 1797681200120201216 |
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| author | Engin Aynacı Gökhan Karakurt |
| author_facet | Engin Aynacı Gökhan Karakurt |
| author_sort | Engin Aynacı |
| collection | DOAJ |
| description | Objective:In our study, we aimed to investigate the long-term effects of the acute phase parameters of C-reactive protein, procalcitonin, D-dimer, lymphocyte, thrombocyte and ferritin on the respiratory function parameters in patients hospitalized due to Coronavirus disease-2019 (COVID-19) pneumonia.Method:The present study was carried out with the retrospective evaluation of patients with COVID-19 pneumonia, who were hospitalized in Medipol University Hospital between March 2020 and June 2021, and who were 6 months to 1 year after discharge. The relationship between pulmonary function test results and acute period laboratory findings of 52 patients who applied for control purposes 6 months after discharge was examined.Results:Diffusing capacity for carbon monoxide (DLCO) (pred) value in 26 patients (50%), total lung capacity (TLC) value in 9 patients (17.3%), and residual volume (RV) (pred) value in 10 patients (19.2%) were below 80%. As a result of multiple linear regression analysis in our study, the maximum D-dimer level and maximum procalcitonin level were determined by DLCO (% pred) (adjusted R2 =0.645; p<0.001), TLC (% pred) (adjusted R2 =0.582; p=0.003) and RV (% pred) (adjusted R2 =0.560; p=0.001) values and were independent determinants in predicting these values.Conclusion:High D-dimer and procalcitonin levels in the acute period in patients with COVID-19 pneumonia may predict losses in respiratory function parameters such as DLCO, TLC, RV in the longer term than 6 months. Long-term follow-up of these patients is important in terms of respiratory function. |
| first_indexed | 2024-03-11T23:41:25Z |
| format | Article |
| id | doaj.art-f2db4e50eebc455a966723c40f0e1209 |
| institution | Directory Open Access Journal |
| issn | 2547-9431 |
| language | English |
| last_indexed | 2024-03-11T23:41:25Z |
| publishDate | 2023-09-01 |
| publisher | Galenos Yayinevi |
| record_format | Article |
| series | Bagcilar Medical Bulletin |
| spelling | doaj.art-f2db4e50eebc455a966723c40f0e12092023-09-19T15:23:17ZengGalenos YayineviBagcilar Medical Bulletin2547-94312023-09-018321021510.4274/BMB.galenos.2023.2023-01-0113049054Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory ParametersEngin Aynacı0Gökhan Karakurt1 Beykent University Faculty of Medicine, Department of Chest Diseases, İstanbul, Turkey Kırklareli Training and Research Hospital, Clinic of Chest Diseases, Kırklareli, Turkey Objective:In our study, we aimed to investigate the long-term effects of the acute phase parameters of C-reactive protein, procalcitonin, D-dimer, lymphocyte, thrombocyte and ferritin on the respiratory function parameters in patients hospitalized due to Coronavirus disease-2019 (COVID-19) pneumonia.Method:The present study was carried out with the retrospective evaluation of patients with COVID-19 pneumonia, who were hospitalized in Medipol University Hospital between March 2020 and June 2021, and who were 6 months to 1 year after discharge. The relationship between pulmonary function test results and acute period laboratory findings of 52 patients who applied for control purposes 6 months after discharge was examined.Results:Diffusing capacity for carbon monoxide (DLCO) (pred) value in 26 patients (50%), total lung capacity (TLC) value in 9 patients (17.3%), and residual volume (RV) (pred) value in 10 patients (19.2%) were below 80%. As a result of multiple linear regression analysis in our study, the maximum D-dimer level and maximum procalcitonin level were determined by DLCO (% pred) (adjusted R2 =0.645; p<0.001), TLC (% pred) (adjusted R2 =0.582; p=0.003) and RV (% pred) (adjusted R2 =0.560; p=0.001) values and were independent determinants in predicting these values.Conclusion:High D-dimer and procalcitonin levels in the acute period in patients with COVID-19 pneumonia may predict losses in respiratory function parameters such as DLCO, TLC, RV in the longer term than 6 months. Long-term follow-up of these patients is important in terms of respiratory function. http://behmedicalbulletin.org/archives/archive-detail/article-preview/tips-for-6-months-after-covd-19-pneumonia-acute-nf/60754 covid-19d-dimerdlco |
| spellingShingle | Engin Aynacı Gökhan Karakurt Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory Parameters Bagcilar Medical Bulletin covid-19 d-dimer dlco |
| title | Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory Parameters |
| title_full | Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory Parameters |
| title_fullStr | Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory Parameters |
| title_full_unstemmed | Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory Parameters |
| title_short | Tips for 6 Months After COVID-19 Pneumonia: Acute Inflammatory Parameters |
| title_sort | tips for 6 months after covid 19 pneumonia acute inflammatory parameters |
| topic | covid-19 d-dimer dlco |
| url |
http://behmedicalbulletin.org/archives/archive-detail/article-preview/tips-for-6-months-after-covd-19-pneumonia-acute-nf/60754
|
| work_keys_str_mv | AT enginaynacı tipsfor6monthsaftercovid19pneumoniaacuteinflammatoryparameters AT gokhankarakurt tipsfor6monthsaftercovid19pneumoniaacuteinflammatoryparameters |