Mechanism and function of the outer membrane channel TolC in multidrug resistance and physiology of enterobacteria

Mechanism and function of the outer membrane channel TolC in multidrug resistance and physiology of enterobacteria

TolC is an archetypal member of the Outer membrane Efflux Protein (OEP) family. These proteins are involved in export of peptide and small molecule toxins across the outer membrane of Gram-negative bacteria. Genomes of some bacteria such as Pseudomonas species contain multiple copies of OEPs. In con...

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Bibliographic Details
Main Authors:	Helen I. Zgurskaya, Ganesh eKrishnamoorthy, Abigail eNtreh, Shuo eLu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2011-09-01
Series:	Frontiers in Microbiology
Subjects:	Oxidative Stress acid tolerance enterobacterial virulence multidrug efflux outer membrane permeability
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fmicb.2011.00189/full

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