Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease
Background: Parkinson’s disease is one of the most common neurodegenerative disorders. While a definitive cure for Parkinson’s disease remains elusive, a range of treatments are available to slow its progression and counteract its symptoms. Transcranial direct current stimulation (tDCS) represents a...
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| Format: | Article |
| Language: | English |
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IMR Press
2024-01-01
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| Series: | Journal of Integrative Neuroscience |
| Subjects: | |
| Online Access: | https://www.imrpress.com/journal/JIN/23/2/10.31083/j.jin2302025 |
| _version_ | 1797291532308447232 |
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| author | Rosa Angela Fabio Rossella Suriano Antonio Gangemi |
| author_facet | Rosa Angela Fabio Rossella Suriano Antonio Gangemi |
| author_sort | Rosa Angela Fabio |
| collection | DOAJ |
| description | Background: Parkinson’s disease is one of the most common neurodegenerative disorders. While a definitive cure for Parkinson’s disease remains elusive, a range of treatments are available to slow its progression and counteract its symptoms. Transcranial direct current stimulation (tDCS) represents a non-invasive method to induce brain plasticity. The aim of this study was to examine the effects of two weeks of tDCS on the left dorsolateral prefrontal cortex (DLPFC) on the neurophysiological functioning of Parkinson’s patients. Methods: Thirty patients aged between 67 and 82 years with Parkinson’s disease participated to the experiment. Fifteen underwent tDCS on the left DLPFC, while fifteen underwent sham tDCS. Neurophysiological functions were assessed before and after tDCS using electroencephalogram methods for alpha and beta band rhythms and P300 event-related potential latency. Results: tDCS led to a reduction in the onset latency of the P300 response and an increase in the power spectrum of the alpha and beta band rhythms. Conclusions: This research enhances our understanding of the potential effects of tDCS in the context of Parkinson’s disease treatment, as the reduction in P300 latency and the increase in alpha and beta bands are associated with improvements in cognitive aspects. |
| first_indexed | 2024-03-07T19:38:09Z |
| format | Article |
| id | doaj.art-f2db8bd7fbf04a9692f185728e5401f0 |
| institution | Directory Open Access Journal |
| issn | 0219-6352 |
| language | English |
| last_indexed | 2024-03-07T19:38:09Z |
| publishDate | 2024-01-01 |
| publisher | IMR Press |
| record_format | Article |
| series | Journal of Integrative Neuroscience |
| spelling | doaj.art-f2db8bd7fbf04a9692f185728e5401f02024-02-29T08:00:15ZengIMR PressJournal of Integrative Neuroscience0219-63522024-01-012322510.31083/j.jin2302025S0219-6352(23)00677-0Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's DiseaseRosa Angela Fabio0Rossella Suriano1Antonio Gangemi2Department of Economics, University of Messina, 98100 Messina, ItalyDepartment of Cognitive, Psychological and Pedagogical Sciences and Cultural Studies, University of Messina, 98100 Messina, ItalyPolyclinic Madonna della Consolazione, 89124 Reggio Calabria, ItalyBackground: Parkinson’s disease is one of the most common neurodegenerative disorders. While a definitive cure for Parkinson’s disease remains elusive, a range of treatments are available to slow its progression and counteract its symptoms. Transcranial direct current stimulation (tDCS) represents a non-invasive method to induce brain plasticity. The aim of this study was to examine the effects of two weeks of tDCS on the left dorsolateral prefrontal cortex (DLPFC) on the neurophysiological functioning of Parkinson’s patients. Methods: Thirty patients aged between 67 and 82 years with Parkinson’s disease participated to the experiment. Fifteen underwent tDCS on the left DLPFC, while fifteen underwent sham tDCS. Neurophysiological functions were assessed before and after tDCS using electroencephalogram methods for alpha and beta band rhythms and P300 event-related potential latency. Results: tDCS led to a reduction in the onset latency of the P300 response and an increase in the power spectrum of the alpha and beta band rhythms. Conclusions: This research enhances our understanding of the potential effects of tDCS in the context of Parkinson’s disease treatment, as the reduction in P300 latency and the increase in alpha and beta bands are associated with improvements in cognitive aspects.https://www.imrpress.com/journal/JIN/23/2/10.31083/j.jin2302025parkinson's diseasetranscranial direct current stimulation (tdcs)electroencephalogram (eeg)p300 event-related potentialalpha and beta band rhythms |
| spellingShingle | Rosa Angela Fabio Rossella Suriano Antonio Gangemi Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease Journal of Integrative Neuroscience parkinson's disease transcranial direct current stimulation (tdcs) electroencephalogram (eeg) p300 event-related potential alpha and beta band rhythms |
| title | Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease |
| title_full | Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease |
| title_fullStr | Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease |
| title_full_unstemmed | Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease |
| title_short | Effects of Transcranial Direct Current Stimulation on Potential P300-Related Events and Alpha and Beta EEG Band Rhythms in Parkinson's Disease |
| title_sort | effects of transcranial direct current stimulation on potential p300 related events and alpha and beta eeg band rhythms in parkinson s disease |
| topic | parkinson's disease transcranial direct current stimulation (tdcs) electroencephalogram (eeg) p300 event-related potential alpha and beta band rhythms |
| url | https://www.imrpress.com/journal/JIN/23/2/10.31083/j.jin2302025 |
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