Low-density hepatitis C virus infectious particles are protected from oxidation by secreted cellular proteins

ABSTRACT Hepatitis C virus (HCV) particles secreted from cells are stable at 37°C, whether the producer cell media contain serum or not. Yet, we found that intracellular HCV particles harvested after freeze-thawing of producer cells are highly unstable upon resuspension in a serum-free medium, indic...

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Detalhes bibliográficos
Main Authors: Christelle Granier, Johan Toesca, Chloé Mialon, Maureen Ritter, Natalia Freitas, Bertrand Boson, Eve-Isabelle Pécheur, François-Loïc Cosset, Solène Denolly
Formato: Artigo
Idioma:English
Publicado em: American Society for Microbiology 2023-10-01
Colecção:mBio
Assuntos:
Acesso em linha:https://journals.asm.org/doi/10.1128/mbio.01549-23