Process optimization for acid-amine coupling: a catalytic approach
Proficient routes were devised for coupling different aromatic/aliphatic acids with amines to form amide linkage using various catalysts. Under the optimized reaction conditions, highest conversion was possible without formation of any by-products. All synthesized compounds were purified us...
Main Authors: | , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Growing Science
2023-01-01
|
Series: | Current Chemistry Letters |
Online Access: | http://www.growingscience.com/ccl/Vol12/ccl_2022_36.pdf |
Summary: | Proficient routes were devised for coupling different aromatic/aliphatic acids with amines to form amide linkage using various catalysts. Under the optimized reaction conditions, highest conversion was possible without formation of any by-products. All synthesized compounds were purified using column chromatography and characterized by mass spectrometry, nuclear magnetic resonance spectrometry and liquid chromatography-mass spectrometric analysis. |
---|---|
ISSN: | 1927-7296 1927-730X |