Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy
We assessed the accuracy of a prototype radiation detector with a built in CMOS amplifier for use in dosimetry for high dose rate brachytherapy. The detectors were fabricated on two substrates of epitaxial high resistivity silicon. The radiation detection performance of prototypes has been tested by...
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MDPI AG
2024-01-01
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| author | Thi Ngoc Hang Bui Matthew Large Joel Poder Joseph Bucci Edoardo Bianco Raffaele Aaron Giampaolo Angelo Rivetti Manuel Da Rocha Rolo Zeljko Pastuovic Thomas Corradino Lucio Pancheri Marco Petasecca |
| author_facet | Thi Ngoc Hang Bui Matthew Large Joel Poder Joseph Bucci Edoardo Bianco Raffaele Aaron Giampaolo Angelo Rivetti Manuel Da Rocha Rolo Zeljko Pastuovic Thomas Corradino Lucio Pancheri Marco Petasecca |
| author_sort | Thi Ngoc Hang Bui |
| collection | DOAJ |
| description | We assessed the accuracy of a prototype radiation detector with a built in CMOS amplifier for use in dosimetry for high dose rate brachytherapy. The detectors were fabricated on two substrates of epitaxial high resistivity silicon. The radiation detection performance of prototypes has been tested by ion beam induced charge (IBIC) microscopy using a 5.5 MeV alpha particle microbeam. We also carried out the HDR Ir-192 radiation source tracking at different depths and angular dose dependence in a water equivalent phantom. The detectors show sensitivities spanning from (5.8 ± 0.021) × 10<sup>−8</sup> to (3.6 ± 0.14) × 10<sup>−8</sup> nC Gy<sup>−1</sup> mCi<sup>−1</sup> mm<sup>−2</sup>. The depth variation of the dose is within 5% with that calculated by TG-43. Higher discrepancies are recorded for 2 mm and 7 mm depths due to the scattering of secondary particles and the perturbation of the radiation field induced in the ceramic/golden package. Dwell positions and dwell time are reconstructed within ±1 mm and 20 ms, respectively. The prototype detectors provide an unprecedented sensitivity thanks to its monolithic amplification stage. Future investigation of this technology will include the optimisation of the packaging technique. |
| first_indexed | 2024-03-08T09:47:14Z |
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| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-03-08T09:47:14Z |
| publishDate | 2024-01-01 |
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| series | Sensors |
| spelling | doaj.art-f2ed7a77e2ab426489484b625036d1ac2024-01-29T14:18:25ZengMDPI AGSensors1424-82202024-01-0124269210.3390/s24020692Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR BrachytherapyThi Ngoc Hang Bui0Matthew Large1Joel Poder2Joseph Bucci3Edoardo Bianco4Raffaele Aaron Giampaolo5Angelo Rivetti6Manuel Da Rocha Rolo7Zeljko Pastuovic8Thomas Corradino9Lucio Pancheri10Marco Petasecca11Centre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, AustraliaCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, AustraliaCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, AustraliaCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, AustraliaDepartment of Electronics and Telecommunications, Polytechnic University of Turin, 10129 Turin, ItalyDepartment of Electronics and Telecommunications, Polytechnic University of Turin, 10129 Turin, ItalyIstituto Nazionale di Fisica Nucleare—Section of Turin, 10125 Turin, ItalyIstituto Nazionale di Fisica Nucleare—Section of Turin, 10125 Turin, ItalyAustralian Nuclear Science and Technology Organisation, Lucas Heights, NSW 2234, AustraliaDepartment of Industrial Engineering, University of Trento, 38123 Trento, ItalyDepartment of Industrial Engineering, University of Trento, 38123 Trento, ItalyCentre for Medical Radiation Physics, University of Wollongong, Wollongong, NSW 2522, AustraliaWe assessed the accuracy of a prototype radiation detector with a built in CMOS amplifier for use in dosimetry for high dose rate brachytherapy. The detectors were fabricated on two substrates of epitaxial high resistivity silicon. The radiation detection performance of prototypes has been tested by ion beam induced charge (IBIC) microscopy using a 5.5 MeV alpha particle microbeam. We also carried out the HDR Ir-192 radiation source tracking at different depths and angular dose dependence in a water equivalent phantom. The detectors show sensitivities spanning from (5.8 ± 0.021) × 10<sup>−8</sup> to (3.6 ± 0.14) × 10<sup>−8</sup> nC Gy<sup>−1</sup> mCi<sup>−1</sup> mm<sup>−2</sup>. The depth variation of the dose is within 5% with that calculated by TG-43. Higher discrepancies are recorded for 2 mm and 7 mm depths due to the scattering of secondary particles and the perturbation of the radiation field induced in the ceramic/golden package. Dwell positions and dwell time are reconstructed within ±1 mm and 20 ms, respectively. The prototype detectors provide an unprecedented sensitivity thanks to its monolithic amplification stage. Future investigation of this technology will include the optimisation of the packaging technique.https://www.mdpi.com/1424-8220/24/2/692brachytherapyCMOSsource trackingactive pixeldosimetryIBIC |
| spellingShingle | Thi Ngoc Hang Bui Matthew Large Joel Poder Joseph Bucci Edoardo Bianco Raffaele Aaron Giampaolo Angelo Rivetti Manuel Da Rocha Rolo Zeljko Pastuovic Thomas Corradino Lucio Pancheri Marco Petasecca Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy Sensors brachytherapy CMOS source tracking active pixel dosimetry IBIC |
| title | Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy |
| title_full | Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy |
| title_fullStr | Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy |
| title_full_unstemmed | Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy |
| title_short | Preliminary Characterization of an Active CMOS Pad Detector for Tracking and Dosimetry in HDR Brachytherapy |
| title_sort | preliminary characterization of an active cmos pad detector for tracking and dosimetry in hdr brachytherapy |
| topic | brachytherapy CMOS source tracking active pixel dosimetry IBIC |
| url | https://www.mdpi.com/1424-8220/24/2/692 |
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