Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysis
Introduction Common mental disorders, including depression, anxiety and related somatic health symptoms, are leading causes of disability worldwide. Especially in low-resource settings, psychosocial interventions delivered by non-specialist providers through task-sharing modalities proved to be vali...
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2023-11-01
|
| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/13/11/e077037.full |
| _version_ | 1797435083832950784 |
|---|---|
| author | Toshi A Furukawa Eirini Karyotaki Pim Cuijpers Vikram Patel Marianna Purgato Davide Papola Marit Sijbrandij Federico Tedeschi Corrado Barbui Efthimiou Orestis |
| author_facet | Toshi A Furukawa Eirini Karyotaki Pim Cuijpers Vikram Patel Marianna Purgato Davide Papola Marit Sijbrandij Federico Tedeschi Corrado Barbui Efthimiou Orestis |
| author_sort | Toshi A Furukawa |
| collection | DOAJ |
| description | Introduction Common mental disorders, including depression, anxiety and related somatic health symptoms, are leading causes of disability worldwide. Especially in low-resource settings, psychosocial interventions delivered by non-specialist providers through task-sharing modalities proved to be valid options to expand access to mental healthcare. However, such interventions are usually eclectic multicomponent interventions consisting of different combinations of evidence-based therapeutic strategies. Which of these various components (or combinations thereof) are more efficacious (and for whom) to reduce common mental disorder symptomatology is yet to be substantiated by evidence.Methods and analysis Comprehensive search was performed in electronic databases MEDLINE, Embase, PsycINFO and the Cochrane Register of Controlled Trials—CENTRAL from database inception to 15 March 2023 to systematically identify all randomised controlled trials that compared any single component or multicomponent psychosocial intervention delivered through the task-sharing modality against any active or inactive control condition in the treatment of adults suffering from common mental disorders. From these trials, individual participant data (IPD) of all measured outcomes and covariates will be collected. We will dismantle psychosocial interventions creating a taxonomy of components and then apply the IPD component network meta-analysis (IPD-cNMA) methodology to assess the efficacy of individual components (or combinations thereof) according to participant-level prognostic factors and effect modifiers.Ethics and dissemination Ethics approval is not applicable for this study since no original data will be collected. Results from this study will be published in peer-reviewed journals and presented at relevant conferences. |
| first_indexed | 2024-03-09T10:42:07Z |
| format | Article |
| id | doaj.art-f2ee90edd21e42b5b13a0e23d94df4de |
| institution | Directory Open Access Journal |
| issn | 2044-6055 |
| language | English |
| last_indexed | 2024-03-09T10:42:07Z |
| publishDate | 2023-11-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj.art-f2ee90edd21e42b5b13a0e23d94df4de2023-12-01T13:40:07ZengBMJ Publishing GroupBMJ Open2044-60552023-11-01131110.1136/bmjopen-2023-077037Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysisToshi A Furukawa0Eirini Karyotaki1Pim Cuijpers2Vikram Patel3Marianna Purgato4Davide Papola5Marit Sijbrandij6Federico Tedeschi7Corrado Barbui8Efthimiou Orestis9Department of Health Promotion and Human Behavior, Kyoto University Graduate School of Medicine/School of Public Health, Kyoto University, Kyoto, JapanDepartment of Clinical, Neuro and Developmental Psychology, WHO Collaborating Centre for Research and Dissemination of Psychological Interventions, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Clinical, Neuro and Developmental Psychology, WHO Collaborating Centre for Research and Dissemination of Psychological Interventions, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USAWHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Science, Section of Psychiatry, University of Verona, Verona, ItalyDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USADepartment of Clinical, Neuro and Developmental Psychology, WHO Collaborating Centre for Research and Dissemination of Psychological Interventions, Amsterdam Public Health research institute, Vrije Universiteit Amsterdam, Amsterdam, The NetherlandsWHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Science, Section of Psychiatry, University of Verona, Verona, ItalyWHO Collaborating Centre for Research and Training in Mental Health and Service Evaluation, Department of Neuroscience, Biomedicine and Movement Science, Section of Psychiatry, University of Verona, Verona, ItalyInstitute of Primary Health Care (BIHAM), University of Bern, Bern, SwitzerlandIntroduction Common mental disorders, including depression, anxiety and related somatic health symptoms, are leading causes of disability worldwide. Especially in low-resource settings, psychosocial interventions delivered by non-specialist providers through task-sharing modalities proved to be valid options to expand access to mental healthcare. However, such interventions are usually eclectic multicomponent interventions consisting of different combinations of evidence-based therapeutic strategies. Which of these various components (or combinations thereof) are more efficacious (and for whom) to reduce common mental disorder symptomatology is yet to be substantiated by evidence.Methods and analysis Comprehensive search was performed in electronic databases MEDLINE, Embase, PsycINFO and the Cochrane Register of Controlled Trials—CENTRAL from database inception to 15 March 2023 to systematically identify all randomised controlled trials that compared any single component or multicomponent psychosocial intervention delivered through the task-sharing modality against any active or inactive control condition in the treatment of adults suffering from common mental disorders. From these trials, individual participant data (IPD) of all measured outcomes and covariates will be collected. We will dismantle psychosocial interventions creating a taxonomy of components and then apply the IPD component network meta-analysis (IPD-cNMA) methodology to assess the efficacy of individual components (or combinations thereof) according to participant-level prognostic factors and effect modifiers.Ethics and dissemination Ethics approval is not applicable for this study since no original data will be collected. Results from this study will be published in peer-reviewed journals and presented at relevant conferences.https://bmjopen.bmj.com/content/13/11/e077037.full |
| spellingShingle | Toshi A Furukawa Eirini Karyotaki Pim Cuijpers Vikram Patel Marianna Purgato Davide Papola Marit Sijbrandij Federico Tedeschi Corrado Barbui Efthimiou Orestis Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysis BMJ Open |
| title | Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysis |
| title_full | Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysis |
| title_fullStr | Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysis |
| title_full_unstemmed | Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysis |
| title_short | Dismantling and personalising task-sharing psychosocial interventions for common mental disorders: a study protocol for an individual participant data component network meta-analysis |
| title_sort | dismantling and personalising task sharing psychosocial interventions for common mental disorders a study protocol for an individual participant data component network meta analysis |
| url | https://bmjopen.bmj.com/content/13/11/e077037.full |
| work_keys_str_mv | AT toshiafurukawa dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT eirinikaryotaki dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT pimcuijpers dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT vikrampatel dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT mariannapurgato dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT davidepapola dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT maritsijbrandij dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT federicotedeschi dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT corradobarbui dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis AT efthimiouorestis dismantlingandpersonalisingtasksharingpsychosocialinterventionsforcommonmentaldisordersastudyprotocolforanindividualparticipantdatacomponentnetworkmetaanalysis |