Gold Nanoparticles: A New Golden Era in Oncology?
In recent years, the spectrum of possible applications of gold in diagnostics and therapeutic approaches in clinical practice has changed significantly, becoming surprisingly broad. Nowadays, gold-based therapeutic agents are used in the therapy of multiple human diseases, ranging from degenerative...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Pharmaceuticals |
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| Online Access: | https://www.mdpi.com/1424-8247/13/8/192 |
| _version_ | 1827710149419073536 |
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| author | Clara Gerosa Guido Crisponi Valeria Marina Nurchi Luca Saba Rosita Cappai Flaviana Cau Gavino Faa Peter Van Eyken Mario Scartozzi Giuseppe Floris Daniela Fanni |
| author_facet | Clara Gerosa Guido Crisponi Valeria Marina Nurchi Luca Saba Rosita Cappai Flaviana Cau Gavino Faa Peter Van Eyken Mario Scartozzi Giuseppe Floris Daniela Fanni |
| author_sort | Clara Gerosa |
| collection | DOAJ |
| description | In recent years, the spectrum of possible applications of gold in diagnostics and therapeutic approaches in clinical practice has changed significantly, becoming surprisingly broad. Nowadays, gold-based therapeutic agents are used in the therapy of multiple human diseases, ranging from degenerative to infectious diseases and, in particular, to cancer. At the basis of these performances of gold, there is the development of new gold-based nanoparticles, characterized by a promising risk/benefit ratio that favors their introduction in clinical trials. Gold nanoparticles appear as attractive elements in nanomedicine, a branch of modern clinical medicine, which combines high selectivity in targeting tumor cells and low toxicity. Thanks to these peculiar characteristics, gold nanoparticles appear as the starting point for the development of new gold-based therapeutic strategies in oncology. Here, the new gold-based therapeutic agents developed in recent years are described, with particular emphasis on the possible applications in clinical practice as anticancer agents, with the aim that their application will give rise to a new golden age in oncology and a breakthrough in the fight against cancer. |
| first_indexed | 2024-03-10T17:33:07Z |
| format | Article |
| id | doaj.art-f2f250fb401c4ca6be421ceee7d5b7a0 |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-10T17:33:07Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-f2f250fb401c4ca6be421ceee7d5b7a02023-11-20T09:57:29ZengMDPI AGPharmaceuticals1424-82472020-08-0113819210.3390/ph13080192Gold Nanoparticles: A New Golden Era in Oncology?Clara Gerosa0Guido Crisponi1Valeria Marina Nurchi2Luca Saba3Rosita Cappai4Flaviana Cau5Gavino Faa6Peter Van Eyken7Mario Scartozzi8Giuseppe Floris9Daniela Fanni10UOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, ItalyDipartimento di Scienze della Vita e dell’Ambiente, University of Cagliari, 09042 Cagliari, ItalyDipartimento di Scienze della Vita e dell’Ambiente, University of Cagliari, 09042 Cagliari, ItalyUOC Radiologia, AOU Cagliari, University of Cagliari, 09042 Cagliari, ItalyDipartimento di Scienze della Vita e dell’Ambiente, University of Cagliari, 09042 Cagliari, ItalyUOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, ItalyUOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, ItalyDepartment of Pathology, Genk Regional Ziekenhuis, 3600 Genk, BelgiumUOC Oncologia Medica, AOU Cagliari, University of Cagliari, 09042 Cagliari, ItalyPathologische Ontleedkunde K.U. Leuven, 3000 Leuven, BelgiumUOC Anatomia Patologica, AOU Cagliari, University of Cagliari, 09124 Cagliari, ItalyIn recent years, the spectrum of possible applications of gold in diagnostics and therapeutic approaches in clinical practice has changed significantly, becoming surprisingly broad. Nowadays, gold-based therapeutic agents are used in the therapy of multiple human diseases, ranging from degenerative to infectious diseases and, in particular, to cancer. At the basis of these performances of gold, there is the development of new gold-based nanoparticles, characterized by a promising risk/benefit ratio that favors their introduction in clinical trials. Gold nanoparticles appear as attractive elements in nanomedicine, a branch of modern clinical medicine, which combines high selectivity in targeting tumor cells and low toxicity. Thanks to these peculiar characteristics, gold nanoparticles appear as the starting point for the development of new gold-based therapeutic strategies in oncology. Here, the new gold-based therapeutic agents developed in recent years are described, with particular emphasis on the possible applications in clinical practice as anticancer agents, with the aim that their application will give rise to a new golden age in oncology and a breakthrough in the fight against cancer.https://www.mdpi.com/1424-8247/13/8/192goldnanoparticlesoncology |
| spellingShingle | Clara Gerosa Guido Crisponi Valeria Marina Nurchi Luca Saba Rosita Cappai Flaviana Cau Gavino Faa Peter Van Eyken Mario Scartozzi Giuseppe Floris Daniela Fanni Gold Nanoparticles: A New Golden Era in Oncology? Pharmaceuticals gold nanoparticles oncology |
| title | Gold Nanoparticles: A New Golden Era in Oncology? |
| title_full | Gold Nanoparticles: A New Golden Era in Oncology? |
| title_fullStr | Gold Nanoparticles: A New Golden Era in Oncology? |
| title_full_unstemmed | Gold Nanoparticles: A New Golden Era in Oncology? |
| title_short | Gold Nanoparticles: A New Golden Era in Oncology? |
| title_sort | gold nanoparticles a new golden era in oncology |
| topic | gold nanoparticles oncology |
| url | https://www.mdpi.com/1424-8247/13/8/192 |
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