Topiramate augmentation in refractory obsessive-compulsive disorder: A randomized, double-blind, placebo-controlled trial

Topiramate augmentation in refractory obsessive-compulsive disorder: A randomized, double-blind, placebo-controlled trial

Background: This study aimed to assess the efficacy of topiramate, a glutamate-modulating agent, in patients with treatment-resistant obsessive-compulsive disorder (OCD) as an adjunct to serotonin reuptake inhibitors (SRIs). Materials and Methods: Thirty-eight patients with refractory OCD, were rand...

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Bibliographic Details
Main Authors: Hamid Afshar, Shahla Akuchekian, Behzad Mahaky, Elham Zarean
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Journal of Research in Medical Sciences
Subjects:
Clinical global impression scale
obsessive-compulsive disorder
randomized controlled trials
topiramate
Yale-Brown obsessive-compulsive scale
Online Access:http://www.jmsjournal.net/article.asp?issn=1735-1995;year=2014;volume=19;issue=10;spage=976;epage=981;aulast=Afshar

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