The Antihistamine Deptropine Induces Hepatoma Cell Death through Blocking Autophagosome-Lysosome Fusion

Some antihistamines have exhibited significant antitumor activity alone or in combination with other therapies in in vitro and clinical studies. However, the underlying mechanisms of how antihistamines inhibit hepatocellular carcinoma proliferation are still unknown. We first screened the antiprolif...

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Bibliographic Details
Main Authors: Yu-Chih Liang, Chi-Ching Chang, Ming-Thau Sheu, Shyr-Yi Lin, Chia-Chen Chung, Chang-Ting Teng, Fat-Moon Suk
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/6/1610

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