CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCE
The paper presents three cohorts of patients with early rheumatoid arthritis (RA) who fell ill at 50 years or older and had a disease duration of 1.5 months to 1 year. To establish its diagnosis, the investigators used classification criteria for each cohort of its period: 1) the 1958 American Rheum...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2020-04-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/2868 |
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| author | A. M. Satybaldyev N. V. Demidova G. I. Gridneva N. Yu. Nikishina E. V. Gerasimova D. A. Gukasian K. A. Kasumova E. L. Luchikhina A. S. Misiyuk T. G. Oskilko O. A. Rumyantseva E. A. Zlepko L. N. Tyurina E. V. Fedorenko N. V. Shornikova E. L. Nasonov |
| author_facet | A. M. Satybaldyev N. V. Demidova G. I. Gridneva N. Yu. Nikishina E. V. Gerasimova D. A. Gukasian K. A. Kasumova E. L. Luchikhina A. S. Misiyuk T. G. Oskilko O. A. Rumyantseva E. A. Zlepko L. N. Tyurina E. V. Fedorenko N. V. Shornikova E. L. Nasonov |
| author_sort | A. M. Satybaldyev |
| collection | DOAJ |
| description | The paper presents three cohorts of patients with early rheumatoid arthritis (RA) who fell ill at 50 years or older and had a disease duration of 1.5 months to 1 year. To establish its diagnosis, the investigators used classification criteria for each cohort of its period: 1) the 1958 American Rheumatism Association (ARA) criteria; 2) the 1987 ARA criteria, and 3) the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria. Along with a change in the criteria, diagnostic methods were improved in this period. Many qualitative laboratory parameters were replaced with their quantitative equivalent; new disease markers (including anti-cyclic citrullinated peptide antibodies) emerged; imaging methods were improved; treatment policies were changed, and targeted biological agents and numerous analogs of the original drugs appeared.Conflicting opinions about the course of RA in older age groups have repeatedly been published in the literature. In the period when the 1958 classification criteria were applied, the opinion that RA has a relatively favorable course was prevalent. Later on, when a more rigid approach to diagnosing RA was applied, there were more and more specialists who considered it to be a severe disease. In this study, the authors try to answer the question of whether the course of the disease changed in the older age groups at the earliest possible date after its onset, by comparing the three cohorts of patients. The findings are discussed. |
| first_indexed | 2024-04-09T22:23:33Z |
| format | Article |
| id | doaj.art-f2fba16abc364e1db86601fe3e792f2d |
| institution | Directory Open Access Journal |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| last_indexed | 2025-03-14T08:04:25Z |
| publishDate | 2020-04-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj.art-f2fba16abc364e1db86601fe3e792f2d2025-03-02T13:23:48ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922020-04-0158214014610.14412/1995-4484-2020-140-1462592CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCEA. M. Satybaldyev0N. V. Demidova1G. I. Gridneva2N. Yu. Nikishina3E. V. Gerasimova4D. A. Gukasian5K. A. Kasumova6E. L. Luchikhina7A. S. Misiyuk8T. G. Oskilko9O. A. Rumyantseva10E. A. Zlepko11L. N. Tyurina12E. V. Fedorenko13N. V. Shornikova14E. L. Nasonov15V.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyM.F. Vladimirsky Moscow Regional Research Clinical InstituteV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of RheumatologyV.A. Nasonova Research Institute of Rheumatology; Joint and Heart Treatment CenterV.A. Nasonova Research Institute of Rheumatology; I.M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaThe paper presents three cohorts of patients with early rheumatoid arthritis (RA) who fell ill at 50 years or older and had a disease duration of 1.5 months to 1 year. To establish its diagnosis, the investigators used classification criteria for each cohort of its period: 1) the 1958 American Rheumatism Association (ARA) criteria; 2) the 1987 ARA criteria, and 3) the 2010 American College of Rheumatology (ACR)/European League Against Rheumatism (EULAR) criteria. Along with a change in the criteria, diagnostic methods were improved in this period. Many qualitative laboratory parameters were replaced with their quantitative equivalent; new disease markers (including anti-cyclic citrullinated peptide antibodies) emerged; imaging methods were improved; treatment policies were changed, and targeted biological agents and numerous analogs of the original drugs appeared.Conflicting opinions about the course of RA in older age groups have repeatedly been published in the literature. In the period when the 1958 classification criteria were applied, the opinion that RA has a relatively favorable course was prevalent. Later on, when a more rigid approach to diagnosing RA was applied, there were more and more specialists who considered it to be a severe disease. In this study, the authors try to answer the question of whether the course of the disease changed in the older age groups at the earliest possible date after its onset, by comparing the three cohorts of patients. The findings are discussed.https://rsp.mediar-press.net/rsp/article/view/2868rheumatoid arthritisolder age periodsclassification criteria for rheumatoid arthritisrheumatoid factoranticyclic citrullinated peptide antibodiesdas28functional classorel all-russian register of rheumatoid arthritis patients |
| spellingShingle | A. M. Satybaldyev N. V. Demidova G. I. Gridneva N. Yu. Nikishina E. V. Gerasimova D. A. Gukasian K. A. Kasumova E. L. Luchikhina A. S. Misiyuk T. G. Oskilko O. A. Rumyantseva E. A. Zlepko L. N. Tyurina E. V. Fedorenko N. V. Shornikova E. L. Nasonov CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCE Научно-практическая ревматология rheumatoid arthritis older age periods classification criteria for rheumatoid arthritis rheumatoid factor anticyclic citrullinated peptide antibodies das28 functional class orel all-russian register of rheumatoid arthritis patients |
| title | CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCE |
| title_full | CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCE |
| title_fullStr | CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCE |
| title_full_unstemmed | CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCE |
| title_short | CLINICAL CHARACTERISTICS OF THREE COHORTS OF PATIENTS WITH EARLY- AND LATE-ONSET RHEUMATOID ARTHRITIS (AT 50 YEARS OR OLDER). GENERALIZATION OF 40 YEARS’ EXPERIENCE |
| title_sort | clinical characteristics of three cohorts of patients with early and late onset rheumatoid arthritis at 50 years or older generalization of 40 years experience |
| topic | rheumatoid arthritis older age periods classification criteria for rheumatoid arthritis rheumatoid factor anticyclic citrullinated peptide antibodies das28 functional class orel all-russian register of rheumatoid arthritis patients |
| url | https://rsp.mediar-press.net/rsp/article/view/2868 |
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