Whole Genome and Transcriptome Sequencing of Two Multi-Drug Resistant Mycobacterium tuberculosis Strains to Facilitate Illustrating Their Virulence in vivo

Whole Genome and Transcriptome Sequencing of Two Multi-Drug Resistant Mycobacterium tuberculosis Strains to Facilitate Illustrating Their Virulence in vivo

Mycobacterium tuberculosis clinical strains usually possess traits different from the laboratory strains like H37Rv, especially those clinical drug resistant strains. With whole genome and transcriptome sequencing, we depicted the feature of two multi-drug resistant Mtb strains in resistance and vir...

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Bibliographic Details
Main Authors: Jun Tang, Zhihao Liu, Ya'nan Shi, Lingjun Zhan, Chuan Qin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
whole genome re-sequencing
RNA-seq
transcriptome sequencing
Mycobacterium tuberculosis
multi-drug resistant
virulence
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00219/full

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