Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy Procedure
Craniospinal irradiation (CSI) is a complex radiation technique employed to treat patients with primitive neuroectodermal tumors such as medulloblastoma or germinative brain tumors with the risk of leptomeningeal spread. In adults, this technique poses a technically challenging planning process beca...
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MDPI AG
2022-09-01
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| Series: | Gels |
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| Online Access: | https://www.mdpi.com/2310-2861/8/9/582 |
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| author | Matheus Antonio da Silveira Juliana Fernandes Pavoni Alexandre Colello Bruno Gustavo Viani Arruda Oswaldo Baffa |
| author_facet | Matheus Antonio da Silveira Juliana Fernandes Pavoni Alexandre Colello Bruno Gustavo Viani Arruda Oswaldo Baffa |
| author_sort | Matheus Antonio da Silveira |
| collection | DOAJ |
| description | Craniospinal irradiation (CSI) is a complex radiation technique employed to treat patients with primitive neuroectodermal tumors such as medulloblastoma or germinative brain tumors with the risk of leptomeningeal spread. In adults, this technique poses a technically challenging planning process because of the complex shape and length of the target volume. Thus, it requires multiple fields and different isocenters to guarantee the primary-tumor dose delivery. Recently, some authors have proposed the use IMRT technique for this planning with the possibility of overlapping adjacent fields. The high-dose delivery complexity demands three-dimensional dosimetry (3DD) to verify this irradiation procedure and motivated this study. We used an optical CT and a radiochromic Fricke-xylenol-orange gel with the addition of formaldehyde (FXO-f) to evaluate the doses delivered at the field junction region of this treatment. We found 96.91% as the mean passing rate using the gamma analysis with 3%/2 mm criteria at the junction region. However, the concentration of fail points in a determined region called attention to this evaluation, indicating the advantages of employing a 3DD technique in complex dose-distribution verifications. |
| first_indexed | 2024-03-09T23:57:58Z |
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| id | doaj.art-f3006b57ab0541c49b69fca1563d949b |
| institution | Directory Open Access Journal |
| issn | 2310-2861 |
| language | English |
| last_indexed | 2024-03-09T23:57:58Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Gels |
| spelling | doaj.art-f3006b57ab0541c49b69fca1563d949b2023-11-23T16:22:29ZengMDPI AGGels2310-28612022-09-018958210.3390/gels8090582Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy ProcedureMatheus Antonio da Silveira0Juliana Fernandes Pavoni1Alexandre Colello Bruno2Gustavo Viani Arruda3Oswaldo Baffa4Departamento de Física, FFCLRP—Universidade de São Paulo, Ribeirão Preto 14040-901, BrazilDepartamento de Física, FFCLRP—Universidade de São Paulo, Ribeirão Preto 14040-901, BrazilHospital das Clínicas da Faculdade de Medicina de Ribeirão Preto–USP, Ribeirão Preto 14015-010, BrazilHospital das Clínicas da Faculdade de Medicina de Ribeirão Preto–USP, Ribeirão Preto 14015-010, BrazilDepartamento de Física, FFCLRP—Universidade de São Paulo, Ribeirão Preto 14040-901, BrazilCraniospinal irradiation (CSI) is a complex radiation technique employed to treat patients with primitive neuroectodermal tumors such as medulloblastoma or germinative brain tumors with the risk of leptomeningeal spread. In adults, this technique poses a technically challenging planning process because of the complex shape and length of the target volume. Thus, it requires multiple fields and different isocenters to guarantee the primary-tumor dose delivery. Recently, some authors have proposed the use IMRT technique for this planning with the possibility of overlapping adjacent fields. The high-dose delivery complexity demands three-dimensional dosimetry (3DD) to verify this irradiation procedure and motivated this study. We used an optical CT and a radiochromic Fricke-xylenol-orange gel with the addition of formaldehyde (FXO-f) to evaluate the doses delivered at the field junction region of this treatment. We found 96.91% as the mean passing rate using the gamma analysis with 3%/2 mm criteria at the junction region. However, the concentration of fail points in a determined region called attention to this evaluation, indicating the advantages of employing a 3DD technique in complex dose-distribution verifications.https://www.mdpi.com/2310-2861/8/9/5823D gel dosimetrycraniospinal irradiationgel dosimetryoptical computed tomographyfricke-xylenol-orange dosimetryintensity modulated radiation therapy (IMRT) |
| spellingShingle | Matheus Antonio da Silveira Juliana Fernandes Pavoni Alexandre Colello Bruno Gustavo Viani Arruda Oswaldo Baffa Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy Procedure Gels 3D gel dosimetry craniospinal irradiation gel dosimetry optical computed tomography fricke-xylenol-orange dosimetry intensity modulated radiation therapy (IMRT) |
| title | Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy Procedure |
| title_full | Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy Procedure |
| title_fullStr | Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy Procedure |
| title_full_unstemmed | Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy Procedure |
| title_short | Three-Dimensional Dosimetry by Optical-CT and Radiochromic Gel Dosimeter of a Multiple Isocenter Craniospinal Radiation Therapy Procedure |
| title_sort | three dimensional dosimetry by optical ct and radiochromic gel dosimeter of a multiple isocenter craniospinal radiation therapy procedure |
| topic | 3D gel dosimetry craniospinal irradiation gel dosimetry optical computed tomography fricke-xylenol-orange dosimetry intensity modulated radiation therapy (IMRT) |
| url | https://www.mdpi.com/2310-2861/8/9/582 |
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