Quantitative Determination of ABT-925 in Human Plasma by On-Line SPE and LC-MS/MS: Validation and Sample Analysis in Phase II Studies

Quantitative Determination of ABT-925 in Human Plasma by On-Line SPE and LC-MS/MS: Validation and Sample Analysis in Phase II Studies

A fully automated 96-well On-Line Solid Phase Extraction (SPE) followed by High Performance Liquid Chromatography (HPLC)-Tandem Mass Spectrometric (MS/MS) method for the determination of ABT-925 (2-{3-[4-(2-tert-Butyl-6-trifluoromethyl-pyrimidin-4-yl)-piperazin-1-yl)-propyl-sulfanyl}-3H-pyrimidin-4-...

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Bibliographic Details
Main Authors:	Katty Wan, Matthew Rieser, Tawakol El-Shourbagy
Format:	Article
Language:	English
Published:	MDPI AG 2010-05-01
Series:	Pharmaceutics
Subjects:	On-line SPE LC-MS/MS multiplexing for high throughput
Online Access:	http://www.mdpi.com/1999-4923/2/2/171/

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