Exosome biopotentiated hydrogel restores damaged skeletal muscle in a porcine model of stress urinary incontinence

Abstract Urinary incontinence afflicts up to 40% of adult women in the United States. Stress urinary incontinence (SUI) accounts for approximately one-third of these cases, precipitating ~200,000 surgical procedures annually. Continence is maintained through the interplay of sub-urethral support and...

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Bibliographic Details
Main Authors: Tyler J. Rolland, Timothy E. Peterson, Ramandeep Takhter, Skylar A. Rizzo, Soulmaz Boroumand, Ao Shi, Tyra A. Witt, Mary Nagel, Cassandra K. Kisby, Sungjo Park, Lois A. Rowe, Christopher R. Paradise, Laura R. E. Becher, Brooke D. Paradise, Paul G. Stalboerger, Emanuel C. Trabuco, Atta Behfar
Format: Article
Language:English
Published: Nature Portfolio 2022-09-01
Series:npj Regenerative Medicine
Online Access:https://doi.org/10.1038/s41536-022-00240-9