Common and distinct functions of mouse Dot1l in the regulation of endothelial transcriptome

Common and distinct functions of mouse Dot1l in the regulation of endothelial transcriptome

Epigenetic mechanisms are mandatory for endothelial called lymphangioblasts during cardiovascular development. Dot1l-mediated gene transcription in mice is essential for the development and function of lymphatic ECs (LECs). The role of Dot1l in the development and function of blood ECs blood endothe...

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Bibliographic Details
Main Authors: Hyunjin Yoo, Hyeonwoo La, Chanhyeok Park, Seonho Yoo, Hyeonji Lee, Hyuk Song, Jeong Tae Do, Youngsok Choi, Kwonho Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
blood endothelial cell
lymphatic endothelial cell
epigenetics
DOT1l
transcriptional regulation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2023.1176115/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2023.1176115/full

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