Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with Hypertension

Hyemin Cho,1,* Sohyun Jeong,2,3,* Cinoo Kang,4 Hee-Jin Kang,1 Suhyun Jang,1 Sunmee Jang1 1College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, Republic of Korea; 2Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA; 3Department of Medic...

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Main Authors: Cho H, Jeong S, Kang C, Kang HJ, Jang S
Format: Article
Language:English
Published: Dove Medical Press 2020-11-01
Series:Patient Preference and Adherence
Subjects:
Online Access:https://www.dovepress.com/risk-factors-and-the-usual-source-of-care-on-non-adherence-to-antihype-peer-reviewed-article-PPA
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author Cho H
Jeong S
Kang C
Kang HJ
Jang S
Jang S
author_facet Cho H
Jeong S
Kang C
Kang HJ
Jang S
Jang S
author_sort Cho H
collection DOAJ
description Hyemin Cho,1,* Sohyun Jeong,2,3,* Cinoo Kang,4 Hee-Jin Kang,1 Suhyun Jang,1 Sunmee Jang1 1College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, Republic of Korea; 2Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA; 3Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA; 4Department of Biostatics and Epidemiology, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea*These authors contributed equally to this workCorrespondence: Sunmee JangCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, 191 Hambakmoero, Yeonsu-Gu, Incheon 21936, South KoreaTel +82-32-820-4941Fax +82-32-820-4829Email smjang@gachon.ac.krBackground: Immigrants are vulnerable to suboptimal health care utilization including non-adherence of medication use. Thus, we aimed to identify the potential risk factors of non-adherence and evaluate whether utilizing a usual source of care was associated with medication adherence in immigrants.Methods: We utilized the Korea National Health Insurance Claims Database between 2012 and 2015. Cases were immigrants who had antihypertensive prescriptions at the time of hypertension diagnosis in 2012. Controls were native-born Koreans with hypertension who were 1:1 matched to immigrants by age, sex, and Charlson comorbidity index. We used the medication possession ratio for three years to assess the adherence to antihypertensive drugs. The likelihood of non-adherence was evaluated between cases and controls by multivariate linear regression models stratified by age, sex, and number of clinic visits. We assessed the potential risk factors of non-adherence in immigrants by multivariate linear regression and logistic regression models, respectively.Results: In total, 4114 immigrants and 4114 matched native-born Koreans with hypertension were included. The mean MPR was significantly lower in immigrants (56% vs 70%, p< 0.0001). Immigrants showed almost two times the level of non-adherence as native-born Koreans (odds ratio [OR], 2.01; 95% confidence interval [CI], 1.83– 2.21). Stratified analyses on non-adherence presented the highest non-adherence (2.28 times) in immigrants in the younger group (30– 49 years old) and the lowest non-adherence in immigrants in 65 and old group where the risk was 1.69 times higher than native Korean with the same age. The absence of a usual source of care significantly increased medication non-adherence by 1.31 to 1.58 times among immigrants.Conclusion: When the number of visited clinics increased, the degree of non-adherence increased consistently. Therefore, the systematization of registering with primary care (a usual source of care) might be a modifiable health care strategy to improve health care outcomes in immigrants.Keywords: usual source of care, hypertension, immigrants, health care strategy
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spelling doaj.art-f30bd517589a405c9afbce6fe38d5a962022-12-21T23:47:44ZengDove Medical PressPatient Preference and Adherence1177-889X2020-11-01Volume 142123213358847Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with HypertensionCho HJeong SKang CKang HJJang SJang SHyemin Cho,1,* Sohyun Jeong,2,3,* Cinoo Kang,4 Hee-Jin Kang,1 Suhyun Jang,1 Sunmee Jang1 1College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, Republic of Korea; 2Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA, USA; 3Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA; 4Department of Biostatics and Epidemiology, Graduate School of Public Health, Seoul National University, Seoul, Republic of Korea*These authors contributed equally to this workCorrespondence: Sunmee JangCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, 191 Hambakmoero, Yeonsu-Gu, Incheon 21936, South KoreaTel +82-32-820-4941Fax +82-32-820-4829Email smjang@gachon.ac.krBackground: Immigrants are vulnerable to suboptimal health care utilization including non-adherence of medication use. Thus, we aimed to identify the potential risk factors of non-adherence and evaluate whether utilizing a usual source of care was associated with medication adherence in immigrants.Methods: We utilized the Korea National Health Insurance Claims Database between 2012 and 2015. Cases were immigrants who had antihypertensive prescriptions at the time of hypertension diagnosis in 2012. Controls were native-born Koreans with hypertension who were 1:1 matched to immigrants by age, sex, and Charlson comorbidity index. We used the medication possession ratio for three years to assess the adherence to antihypertensive drugs. The likelihood of non-adherence was evaluated between cases and controls by multivariate linear regression models stratified by age, sex, and number of clinic visits. We assessed the potential risk factors of non-adherence in immigrants by multivariate linear regression and logistic regression models, respectively.Results: In total, 4114 immigrants and 4114 matched native-born Koreans with hypertension were included. The mean MPR was significantly lower in immigrants (56% vs 70%, p< 0.0001). Immigrants showed almost two times the level of non-adherence as native-born Koreans (odds ratio [OR], 2.01; 95% confidence interval [CI], 1.83– 2.21). Stratified analyses on non-adherence presented the highest non-adherence (2.28 times) in immigrants in the younger group (30– 49 years old) and the lowest non-adherence in immigrants in 65 and old group where the risk was 1.69 times higher than native Korean with the same age. The absence of a usual source of care significantly increased medication non-adherence by 1.31 to 1.58 times among immigrants.Conclusion: When the number of visited clinics increased, the degree of non-adherence increased consistently. Therefore, the systematization of registering with primary care (a usual source of care) might be a modifiable health care strategy to improve health care outcomes in immigrants.Keywords: usual source of care, hypertension, immigrants, health care strategyhttps://www.dovepress.com/risk-factors-and-the-usual-source-of-care-on-non-adherence-to-antihype-peer-reviewed-article-PPAusual source of carehypertensionimmigrantshealth care strategy
spellingShingle Cho H
Jeong S
Kang C
Kang HJ
Jang S
Jang S
Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with Hypertension
Patient Preference and Adherence
usual source of care
hypertension
immigrants
health care strategy
title Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with Hypertension
title_full Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with Hypertension
title_fullStr Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with Hypertension
title_full_unstemmed Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with Hypertension
title_short Risk Factors and the Usual Source of Care on Non-Adherence to Antihypertensive Drugs in Immigrants with Hypertension
title_sort risk factors and the usual source of care on non adherence to antihypertensive drugs in immigrants with hypertension
topic usual source of care
hypertension
immigrants
health care strategy
url https://www.dovepress.com/risk-factors-and-the-usual-source-of-care-on-non-adherence-to-antihype-peer-reviewed-article-PPA
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