Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation
Mounir A Khalifa,1,2 Waleed A Allam,1,2 Mohamed S Shaheen2,31Ophthalmology Department, Tanta University Eye Hospital, Tanta, Egypt; 2Horus Vision Correction Center, Alexandria, Egypt; 3Ophthalmology Department, Alexandria University, Alexandria, EgyptPurpose: To investigate the efficacy and predicta...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2012-12-01
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| Series: | Clinical Ophthalmology |
| Online Access: | http://www.dovepress.com/visual-outcome-after-correcting-the-refractive-error-of-large-pupil-pa-a11661 |
| _version_ | 1831716833701396480 |
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| author | Khalifa MA Allam WA Shaheen MS |
| author_facet | Khalifa MA Allam WA Shaheen MS |
| author_sort | Khalifa MA |
| collection | DOAJ |
| description | Mounir A Khalifa,1,2 Waleed A Allam,1,2 Mohamed S Shaheen2,31Ophthalmology Department, Tanta University Eye Hospital, Tanta, Egypt; 2Horus Vision Correction Center, Alexandria, Egypt; 3Ophthalmology Department, Alexandria University, Alexandria, EgyptPurpose: To investigate the efficacy and predictability of wavefront-guided laser in situ keratomileusis (LASIK) treatments using the iris registration (IR) technology for the correction of refractive errors in patients with large pupils.Setting: Horus Vision Correction Center, Alexandria, Egypt.Methods: Prospective noncomparative study including a total of 52 eyes of 30 consecutive laser refractive correction candidates with large mesopic pupil diameters and myopia or myopic astigmatism. Wavefront-guided LASIK was performed in all cases using the VISX STAR S4 IR excimer laser platform. Visual, refractive, aberrometric and mesopic contrast sensitivity (CS) outcomes were evaluated during a 6-month follow-up.Results: Mean mesopic pupil diameter ranged from 8.0 mm to 9.4 mm. A significant improvement in uncorrected distance visual acuity (UCDVA) (P < 0.01) was found postoperatively, which was consistent with a significant refractive correction (P < 0.01). No significant change was detected in corrected distance visual acuity (CDVA) (P = 0.11). Efficacy index (the ratio of postoperative UCDVA to preoperative CDVA) and safety index (the ratio of postoperative CDVA to preoperative CDVA) were calculated. Mean efficacy and safety indices were 1.06 ± 0.33 and 1.05 ± 0.18, respectively, and 92.31% of eyes had a postoperative spherical equivalent within ±0.50 diopters (D). Manifest refractive spherical equivalent improved significantly (P < 0.05) from a preoperative level of −3.1 ± 1.6 D (range −6.6 to 0 D) to −0.1 ± 0.2 D (range −1.3 to 0.1 D) at 6 months postoperative. No significant changes were found in mesopic CS (P ≥ 0.08), except CS for three cycles/degree, which improved significantly (P = 0.02). Magnitudes of primary coma and trefoil did not change significantly (P ≥ 0.34), with a small but statistically significant increase in primary spherical aberration.Conclusion: Wavefront-guided LASIK provides an effective correction of low to moderate myopia or myopic astigmatism in large pupil patients without deterioration of visual quality.Keywords: large pupil, wavefront, LASIK |
| first_indexed | 2024-12-21T00:47:12Z |
| format | Article |
| id | doaj.art-f30dc81fbb964acd9341bccfaf8910e4 |
| institution | Directory Open Access Journal |
| issn | 1177-5467 1177-5483 |
| language | English |
| last_indexed | 2024-12-21T00:47:12Z |
| publishDate | 2012-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj.art-f30dc81fbb964acd9341bccfaf8910e42022-12-21T19:21:30ZengDove Medical PressClinical Ophthalmology1177-54671177-54832012-12-012012default20012011Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablationKhalifa MAAllam WAShaheen MSMounir A Khalifa,1,2 Waleed A Allam,1,2 Mohamed S Shaheen2,31Ophthalmology Department, Tanta University Eye Hospital, Tanta, Egypt; 2Horus Vision Correction Center, Alexandria, Egypt; 3Ophthalmology Department, Alexandria University, Alexandria, EgyptPurpose: To investigate the efficacy and predictability of wavefront-guided laser in situ keratomileusis (LASIK) treatments using the iris registration (IR) technology for the correction of refractive errors in patients with large pupils.Setting: Horus Vision Correction Center, Alexandria, Egypt.Methods: Prospective noncomparative study including a total of 52 eyes of 30 consecutive laser refractive correction candidates with large mesopic pupil diameters and myopia or myopic astigmatism. Wavefront-guided LASIK was performed in all cases using the VISX STAR S4 IR excimer laser platform. Visual, refractive, aberrometric and mesopic contrast sensitivity (CS) outcomes were evaluated during a 6-month follow-up.Results: Mean mesopic pupil diameter ranged from 8.0 mm to 9.4 mm. A significant improvement in uncorrected distance visual acuity (UCDVA) (P < 0.01) was found postoperatively, which was consistent with a significant refractive correction (P < 0.01). No significant change was detected in corrected distance visual acuity (CDVA) (P = 0.11). Efficacy index (the ratio of postoperative UCDVA to preoperative CDVA) and safety index (the ratio of postoperative CDVA to preoperative CDVA) were calculated. Mean efficacy and safety indices were 1.06 ± 0.33 and 1.05 ± 0.18, respectively, and 92.31% of eyes had a postoperative spherical equivalent within ±0.50 diopters (D). Manifest refractive spherical equivalent improved significantly (P < 0.05) from a preoperative level of −3.1 ± 1.6 D (range −6.6 to 0 D) to −0.1 ± 0.2 D (range −1.3 to 0.1 D) at 6 months postoperative. No significant changes were found in mesopic CS (P ≥ 0.08), except CS for three cycles/degree, which improved significantly (P = 0.02). Magnitudes of primary coma and trefoil did not change significantly (P ≥ 0.34), with a small but statistically significant increase in primary spherical aberration.Conclusion: Wavefront-guided LASIK provides an effective correction of low to moderate myopia or myopic astigmatism in large pupil patients without deterioration of visual quality.Keywords: large pupil, wavefront, LASIKhttp://www.dovepress.com/visual-outcome-after-correcting-the-refractive-error-of-large-pupil-pa-a11661 |
| spellingShingle | Khalifa MA Allam WA Shaheen MS Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation Clinical Ophthalmology |
| title | Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_full | Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_fullStr | Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_full_unstemmed | Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_short | Visual outcome after correcting the refractive error of large pupil patients with wavefront-guided ablation |
| title_sort | visual outcome after correcting the refractive error of large pupil patients with wavefront guided ablation |
| url | http://www.dovepress.com/visual-outcome-after-correcting-the-refractive-error-of-large-pupil-pa-a11661 |
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