Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment
Experiments on event-related electroencephalographic oscillations in aged people typically include blocks of cognitive tasks with a few minutes of interval between them. The present exploratory study tested the effect of being engaged on cognitive tasks over the resting state cortical arousal after...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Aging Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fnagi.2022.907130/full |
| _version_ | 1818485964310315008 |
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| author | Alba Fernández Giuseppe Noce Claudio Del Percio Diego Pinal Fernando Díaz Cristina Lojo-Seoane Montserrat Zurrón Claudio Babiloni Claudio Babiloni |
| author_facet | Alba Fernández Giuseppe Noce Claudio Del Percio Diego Pinal Fernando Díaz Cristina Lojo-Seoane Montserrat Zurrón Claudio Babiloni Claudio Babiloni |
| author_sort | Alba Fernández |
| collection | DOAJ |
| description | Experiments on event-related electroencephalographic oscillations in aged people typically include blocks of cognitive tasks with a few minutes of interval between them. The present exploratory study tested the effect of being engaged on cognitive tasks over the resting state cortical arousal after task completion, and whether it differs according to the level of the participant’s cognitive decline. To investigate this issue, we used a local database including data in 30 healthy cognitively unimpaired (CU) persons and 40 matched patients with amnestic mild cognitive impairment (aMCI). They had been involved in 2 memory tasks for about 40 min and underwent resting-state electroencephalographic (rsEEG) recording after 5 min from the task end. eLORETA freeware estimated rsEEG alpha source activity as an index of general cortical arousal. In the CU but not aMCI group, there was a negative correlation between memory tasks performance and posterior rsEEG alpha source activity. The better the memory tasks performance, the lower the posterior alpha activity (i.e., higher cortical arousal). There was also a negative correlation between neuropsychological test scores of global cognitive status and alpha source activity. These results suggest that engagement in memory tasks may perturb background brain arousal for more than 5 min after the tasks end, and that this effect are dependent on participants global cognitive status. Future studies in CU and aMCI groups may cross-validate and extend these results with experiments including (1) rsEEG recordings before memory tasks and (2) post-tasks rsEEG recordings after 5, 15, and 30 min. |
| first_indexed | 2024-12-10T16:16:36Z |
| format | Article |
| id | doaj.art-f310ced2d128426e874bc399675fdcbe |
| institution | Directory Open Access Journal |
| issn | 1663-4365 |
| language | English |
| last_indexed | 2024-12-10T16:16:36Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Aging Neuroscience |
| spelling | doaj.art-f310ced2d128426e874bc399675fdcbe2022-12-22T01:41:58ZengFrontiers Media S.A.Frontiers in Aging Neuroscience1663-43652022-08-011410.3389/fnagi.2022.907130907130Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairmentAlba Fernández0Giuseppe Noce1Claudio Del Percio2Diego Pinal3Fernando Díaz4Cristina Lojo-Seoane5Montserrat Zurrón6Claudio Babiloni7Claudio Babiloni8Departamento de Psicoloxía Clínica e Psicobioloxía, Facultade de Psicoloxía, Universidade de Santiago de Compostela, Santiago de Compostela, SpainIRCCS Synlab SDN, Naples, ItalyDepartment of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, Rome, ItalyPsychological Neuroscience Lab, Escola de Psicologia, Universidade do Minho, Braga, PortugalDepartamento de Psicoloxía Clínica e Psicobioloxía, Facultade de Psicoloxía, Universidade de Santiago de Compostela, Santiago de Compostela, SpainDepartamento de Psicoloxía Evolutiva e da Educación, Facultade de Psicoloxía, Universidade de Santiago de Compostela, Santiago de Compostela, SpainDepartamento de Psicoloxía Clínica e Psicobioloxía, Facultade de Psicoloxía, Universidade de Santiago de Compostela, Santiago de Compostela, SpainDepartment of Physiology and Pharmacology “V. Erspamer”, Sapienza University of Rome, Rome, ItalySan Raffaele Cassino, Cassino, ItalyExperiments on event-related electroencephalographic oscillations in aged people typically include blocks of cognitive tasks with a few minutes of interval between them. The present exploratory study tested the effect of being engaged on cognitive tasks over the resting state cortical arousal after task completion, and whether it differs according to the level of the participant’s cognitive decline. To investigate this issue, we used a local database including data in 30 healthy cognitively unimpaired (CU) persons and 40 matched patients with amnestic mild cognitive impairment (aMCI). They had been involved in 2 memory tasks for about 40 min and underwent resting-state electroencephalographic (rsEEG) recording after 5 min from the task end. eLORETA freeware estimated rsEEG alpha source activity as an index of general cortical arousal. In the CU but not aMCI group, there was a negative correlation between memory tasks performance and posterior rsEEG alpha source activity. The better the memory tasks performance, the lower the posterior alpha activity (i.e., higher cortical arousal). There was also a negative correlation between neuropsychological test scores of global cognitive status and alpha source activity. These results suggest that engagement in memory tasks may perturb background brain arousal for more than 5 min after the tasks end, and that this effect are dependent on participants global cognitive status. Future studies in CU and aMCI groups may cross-validate and extend these results with experiments including (1) rsEEG recordings before memory tasks and (2) post-tasks rsEEG recordings after 5, 15, and 30 min.https://www.frontiersin.org/articles/10.3389/fnagi.2022.907130/fullresting state EEG poweralpha oscillationscortical arousalmild cognitive impairmentcognitive engagementmemory |
| spellingShingle | Alba Fernández Giuseppe Noce Claudio Del Percio Diego Pinal Fernando Díaz Cristina Lojo-Seoane Montserrat Zurrón Claudio Babiloni Claudio Babiloni Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment Frontiers in Aging Neuroscience resting state EEG power alpha oscillations cortical arousal mild cognitive impairment cognitive engagement memory |
| title | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
| title_full | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
| title_fullStr | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
| title_full_unstemmed | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
| title_short | Resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
| title_sort | resting state electroencephalographic rhythms are affected by immediately preceding memory demands in cognitively unimpaired elderly and patients with mild cognitive impairment |
| topic | resting state EEG power alpha oscillations cortical arousal mild cognitive impairment cognitive engagement memory |
| url | https://www.frontiersin.org/articles/10.3389/fnagi.2022.907130/full |
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