Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma
Objective: To evaluate the clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma (PCNSL). Methods: We retrospectively reviewed the clinical data of 8 patients who were considered suspected cases of P...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844022034508 |
| _version_ | 1797960935429636096 |
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| author | Yong Tang Yan Shi Ling Wang Zheng-ting Qian You-wu Fan He-Ming Wu Xiang Li |
| author_facet | Yong Tang Yan Shi Ling Wang Zheng-ting Qian You-wu Fan He-Ming Wu Xiang Li |
| author_sort | Yong Tang |
| collection | DOAJ |
| description | Objective: To evaluate the clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma (PCNSL). Methods: We retrospectively reviewed the clinical data of 8 patients who were considered suspected cases of PCNSL by multimodal imaging techniques. The final pathologic diagnosis were determined by the frameless robotic stereotactic biopsy. The postoperative related complications and pathological results were analyzed. Results: All patients underwent biopsies under general anesthesia with an average surgery time of 29.5 ± 4.5 min. The final pathological diagnostic accordant rate with the preoperative ones was 100%, and the pathologic examination of our patients showed features of diffuse large B-cell lymphoma. During the surgery, one patient suffered intratumoral hemorrhage without leading to serious cerebral edema, and conservative treatment was given. There was no death occurring during the study, and there were no significant differences in the Karnofsky Performance Scale Scores of all patients before and after surgery. Finally, they were transferred to the hematology department for standardized chemoradiotherapy according to the pathological results of PCNSL. Conclusion: This study shows that it may play a vital role in the early diagnosis of PCNSL with the technique of multimodal imaging. The technique of frameless robotic stereotactic biopsy for obtaining the pathology outcomes in suspected PCNSL patients has the advantages of safety, efficiency, and minimally invasiveness. |
| first_indexed | 2024-04-11T00:51:43Z |
| format | Article |
| id | doaj.art-f3158caeb1e24ba9aaba80fc52c9c48b |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-04-11T00:51:43Z |
| publishDate | 2022-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-f3158caeb1e24ba9aaba80fc52c9c48b2023-01-05T08:39:06ZengElsevierHeliyon2405-84402022-12-01812e12162Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphomaYong Tang0Yan Shi1Ling Wang2Zheng-ting Qian3You-wu Fan4He-Ming Wu5Xiang Li6Department of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, ChinaDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, ChinaDepartment of Planning and Information, Jiangsu Commission of Health, Nanjing 210008, ChinaDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, ChinaDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, ChinaDepartment of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China; Corresponding author.Department of Neurosurgery, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China; Corresponding author.Objective: To evaluate the clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma (PCNSL). Methods: We retrospectively reviewed the clinical data of 8 patients who were considered suspected cases of PCNSL by multimodal imaging techniques. The final pathologic diagnosis were determined by the frameless robotic stereotactic biopsy. The postoperative related complications and pathological results were analyzed. Results: All patients underwent biopsies under general anesthesia with an average surgery time of 29.5 ± 4.5 min. The final pathological diagnostic accordant rate with the preoperative ones was 100%, and the pathologic examination of our patients showed features of diffuse large B-cell lymphoma. During the surgery, one patient suffered intratumoral hemorrhage without leading to serious cerebral edema, and conservative treatment was given. There was no death occurring during the study, and there were no significant differences in the Karnofsky Performance Scale Scores of all patients before and after surgery. Finally, they were transferred to the hematology department for standardized chemoradiotherapy according to the pathological results of PCNSL. Conclusion: This study shows that it may play a vital role in the early diagnosis of PCNSL with the technique of multimodal imaging. The technique of frameless robotic stereotactic biopsy for obtaining the pathology outcomes in suspected PCNSL patients has the advantages of safety, efficiency, and minimally invasiveness.http://www.sciencedirect.com/science/article/pii/S2405844022034508Primary central nervous system lymphomaStereotaxicSurgical roboticsNeedle biopsyMultimodal imaging |
| spellingShingle | Yong Tang Yan Shi Ling Wang Zheng-ting Qian You-wu Fan He-Ming Wu Xiang Li Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma Heliyon Primary central nervous system lymphoma Stereotaxic Surgical robotics Needle biopsy Multimodal imaging |
| title | Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma |
| title_full | Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma |
| title_fullStr | Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma |
| title_full_unstemmed | Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma |
| title_short | Preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma |
| title_sort | preliminary clinical application of multimodal imaging combined with frameless robotic stereotactic biopsy in the diagnosis of primary central nervous system lymphoma |
| topic | Primary central nervous system lymphoma Stereotaxic Surgical robotics Needle biopsy Multimodal imaging |
| url | http://www.sciencedirect.com/science/article/pii/S2405844022034508 |
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