he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis
The goal: to investigate the process of angiogenesis by determining the level of vascular endothelial growth factor (VEGF) in the blood serum of patients with lichen planus (CPL) and psoriasis. Material and Methods. The study included 50 patients with CPL, 62 patients with psoriasis and 36 were in t...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Saratov State Medical University
2014-09-01
|
| Series: | Саратовский научно-медицинский журнал |
| Subjects: | |
| Online Access: | http://www.ssmj.ru/system/files/2014_03-01_539-542.pdf |
| _version_ | 1818876915564412928 |
|---|---|
| author | Artemina Е.М. Shtoda U.М. Slesarenko N.A. Bakulev A.L. Utz S.R. |
| author_facet | Artemina Е.М. Shtoda U.М. Slesarenko N.A. Bakulev A.L. Utz S.R. |
| author_sort | Artemina Е.М. |
| collection | DOAJ |
| description | The goal: to investigate the process of angiogenesis by determining the level of vascular endothelial growth factor (VEGF) in the blood serum of patients with lichen planus (CPL) and psoriasis. Material and Methods. The study included 50 patients with CPL, 62 patients with psoriasis and 36 were in the control group of healthy individuals. All of the participants were to determine the level of VEGF in a blood serum before treatment. Results. Patients with CPL had an increase in the level of VEGF in serum prior to 1992 pg/ml, in the patients with psoriasis — up to 1748.8 pg/ml. Level of VEGF in healthy individuals ranged from 37 to 475 pg/ml. Conclusion. When the CPL and psoriasis excessive angiogenesis is observed, elevated levels of VEGF in the serum of these patients and it is possible that vascular normalization such element of pathogenesis of psoriasis and CPL lead to stable remission of these dermatoses. |
| first_indexed | 2024-12-19T13:49:59Z |
| format | Article |
| id | doaj.art-f3180e1888ed4c43a557277dd05d5974 |
| institution | Directory Open Access Journal |
| issn | 2076-2518 |
| language | Russian |
| last_indexed | 2024-12-19T13:49:59Z |
| publishDate | 2014-09-01 |
| publisher | Saratov State Medical University |
| record_format | Article |
| series | Саратовский научно-медицинский журнал |
| spelling | doaj.art-f3180e1888ed4c43a557277dd05d59742022-12-21T20:18:46ZrusSaratov State Medical UniversityСаратовский научно-медицинский журнал2076-25182014-09-011035395423809he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasisArtemina Е.М.0Shtoda U.М.1Slesarenko N.A.2Bakulev A.L.3Utz S.R.4Saratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversitySaratov State Medical UniversityThe goal: to investigate the process of angiogenesis by determining the level of vascular endothelial growth factor (VEGF) in the blood serum of patients with lichen planus (CPL) and psoriasis. Material and Methods. The study included 50 patients with CPL, 62 patients with psoriasis and 36 were in the control group of healthy individuals. All of the participants were to determine the level of VEGF in a blood serum before treatment. Results. Patients with CPL had an increase in the level of VEGF in serum prior to 1992 pg/ml, in the patients with psoriasis — up to 1748.8 pg/ml. Level of VEGF in healthy individuals ranged from 37 to 475 pg/ml. Conclusion. When the CPL and psoriasis excessive angiogenesis is observed, elevated levels of VEGF in the serum of these patients and it is possible that vascular normalization such element of pathogenesis of psoriasis and CPL lead to stable remission of these dermatoses.http://www.ssmj.ru/system/files/2014_03-01_539-542.pdflichen planuspsoriasis |
| spellingShingle | Artemina Е.М. Shtoda U.М. Slesarenko N.A. Bakulev A.L. Utz S.R. he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis Саратовский научно-медицинский журнал lichen planus psoriasis |
| title | he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis |
| title_full | he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis |
| title_fullStr | he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis |
| title_full_unstemmed | he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis |
| title_short | he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis |
| title_sort | he role of vascular endothelial growth factor in the pathogenesis of lichen planus and psoriasis |
| topic | lichen planus psoriasis |
| url | http://www.ssmj.ru/system/files/2014_03-01_539-542.pdf |
| work_keys_str_mv | AT arteminaem heroleofvascularendothelialgrowthfactorinthepathogenesisoflichenplanusandpsoriasis AT shtodaum heroleofvascularendothelialgrowthfactorinthepathogenesisoflichenplanusandpsoriasis AT slesarenkona heroleofvascularendothelialgrowthfactorinthepathogenesisoflichenplanusandpsoriasis AT bakuleval heroleofvascularendothelialgrowthfactorinthepathogenesisoflichenplanusandpsoriasis AT utzsr heroleofvascularendothelialgrowthfactorinthepathogenesisoflichenplanusandpsoriasis |