The next generation of biopanning: next gen sequencing improves analysis of bacterial display libraries

The next generation of biopanning: next gen sequencing improves analysis of bacterial display libraries

Abstract Background Bacterial surface display libraries are a popular tool for novel ligand discovery due to their ease of manipulation and rapid growth rates. These libraries typically express a scaffold protein embedded within the outer membrane with a short, surface-exposed peptide that is either...

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Bibliographic Details
Main Authors: Sarah D. Stellwagen, Deborah A. Sarkes, Bryn L. Adams, Mia A. Hunt, Rebecca L. Renberg, Margaret M. Hurley, Dimitra N. Stratis-Cullum
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Biotechnology
Subjects:
Bacterial display
Directed evolution
Peptide display
Biopanning
NGS
Online Access:https://doi.org/10.1186/s12896-019-0577-8

Internet

https://doi.org/10.1186/s12896-019-0577-8

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