ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brands
Abstract There are many glass ionomer cements available on the Brazilian market for Atraumatic Restorative Treatment (ART), however, there is still a gap in the literature regarding their cost-effectiveness. Objectives To evaluate the influence of restorative materials (Ketac Molar, 3M ESPE; and V...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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University of São Paulo
2022-11-01
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| Series: | Journal of Applied Oral Science |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572022000100441&tlng=en |
| _version_ | 1798023352957272064 |
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| author | Isabel Cristina OLEGÁRIO Anna Luiza de Brito Pacheco FURLAN Caroline Mariano LAUX Daniela HESSE Clarissa Calil BONIFÁCIO José Carlos Pettorossi IMPARATO Daniela Prócida RAGGIO |
| author_facet | Isabel Cristina OLEGÁRIO Anna Luiza de Brito Pacheco FURLAN Caroline Mariano LAUX Daniela HESSE Clarissa Calil BONIFÁCIO José Carlos Pettorossi IMPARATO Daniela Prócida RAGGIO |
| author_sort | Isabel Cristina OLEGÁRIO |
| collection | DOAJ |
| description | Abstract There are many glass ionomer cements available on the Brazilian market for Atraumatic Restorative Treatment (ART), however, there is still a gap in the literature regarding their cost-effectiveness. Objectives To evaluate the influence of restorative materials (Ketac Molar, 3M ESPE; and Vitro Molar, Nova DFL) in the two-year survival rate and cost-effectiveness of occluso-proximal ART restorations in primary molars. Methodology A total of 117 children (aged four to eight years) with at least one occluso-proximal carious lesion in primary molars were selected and randomly divided in treatment groups (KM or VM) in this parallel randomized controlled trial. Treatments followed ART premises and were conducted in public schools by trained operators in Barueri, Brazil. A trained, calibrated, and blinded examiner performed the evaluations after two, six, 12, and 24 months (k=0.92). Kaplan-Meier survival analysis was used to estimate restoration survival and Cox regression was used to test the association with clinical factors (α=5%). For cost analysis, material and professional costs were considered. Monte Carlo analysis was used to generate a cost-effectiveness plane and bootstrapping was used to compare material costs over the years. Results The overall survival rate was 36.9% after two years (48.6% for KM and 25.4% for VM). Restorations with VM failed more than those with KM (HR=1.70; 95% CI=1.06–2.73; p=0.027). VM presented lower initial cost, but no difference was observed between groups considering the two-year incremental cost. Conclusion After a two-year evaluation, KM proved to be a better option than VM for occluso-proximal ART restorations in primary molars. ClinicalTrials.gov: NCT02267720 |
| first_indexed | 2024-04-11T17:46:03Z |
| format | Article |
| id | doaj.art-f31aa9884a8f4666906e27b23770506a |
| institution | Directory Open Access Journal |
| issn | 1678-7765 |
| language | English |
| last_indexed | 2024-04-11T17:46:03Z |
| publishDate | 2022-11-01 |
| publisher | University of São Paulo |
| record_format | Article |
| series | Journal of Applied Oral Science |
| spelling | doaj.art-f31aa9884a8f4666906e27b23770506a2022-12-22T04:11:23ZengUniversity of São PauloJournal of Applied Oral Science1678-77652022-11-013010.1590/1678-7757-2022-0148ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brandsIsabel Cristina OLEGÁRIOhttps://orcid.org/0000-0003-2262-8061Anna Luiza de Brito Pacheco FURLANhttps://orcid.org/0000-0003-4064-6749Caroline Mariano LAUXhttps://orcid.org/0000-0002-5748-0688Daniela HESSEhttps://orcid.org/0000-0002-0912-4152Clarissa Calil BONIFÁCIOhttps://orcid.org/0000-0001-6515-2927José Carlos Pettorossi IMPARATOhttps://orcid.org/0000-0002-1990-2851Daniela Prócida RAGGIOhttps://orcid.org/0000-0002-0048-2068Abstract There are many glass ionomer cements available on the Brazilian market for Atraumatic Restorative Treatment (ART), however, there is still a gap in the literature regarding their cost-effectiveness. Objectives To evaluate the influence of restorative materials (Ketac Molar, 3M ESPE; and Vitro Molar, Nova DFL) in the two-year survival rate and cost-effectiveness of occluso-proximal ART restorations in primary molars. Methodology A total of 117 children (aged four to eight years) with at least one occluso-proximal carious lesion in primary molars were selected and randomly divided in treatment groups (KM or VM) in this parallel randomized controlled trial. Treatments followed ART premises and were conducted in public schools by trained operators in Barueri, Brazil. A trained, calibrated, and blinded examiner performed the evaluations after two, six, 12, and 24 months (k=0.92). Kaplan-Meier survival analysis was used to estimate restoration survival and Cox regression was used to test the association with clinical factors (α=5%). For cost analysis, material and professional costs were considered. Monte Carlo analysis was used to generate a cost-effectiveness plane and bootstrapping was used to compare material costs over the years. Results The overall survival rate was 36.9% after two years (48.6% for KM and 25.4% for VM). Restorations with VM failed more than those with KM (HR=1.70; 95% CI=1.06–2.73; p=0.027). VM presented lower initial cost, but no difference was observed between groups considering the two-year incremental cost. Conclusion After a two-year evaluation, KM proved to be a better option than VM for occluso-proximal ART restorations in primary molars. ClinicalTrials.gov: NCT02267720http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572022000100441&tlng=enAtraumatic Restorative TreatmentGlass ionomer cementClinical trialCost-effectivenessRestoration survival percentagePrimary teethPediatric dentistry |
| spellingShingle | Isabel Cristina OLEGÁRIO Anna Luiza de Brito Pacheco FURLAN Caroline Mariano LAUX Daniela HESSE Clarissa Calil BONIFÁCIO José Carlos Pettorossi IMPARATO Daniela Prócida RAGGIO ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brands Journal of Applied Oral Science Atraumatic Restorative Treatment Glass ionomer cement Clinical trial Cost-effectiveness Restoration survival percentage Primary teeth Pediatric dentistry |
| title | ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brands |
| title_full | ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brands |
| title_fullStr | ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brands |
| title_full_unstemmed | ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brands |
| title_short | ART restorations for occluso-proximal cavities in primary molars: a two-year survival and cost analysis of an RCT comparing two GIC brands |
| title_sort | art restorations for occluso proximal cavities in primary molars a two year survival and cost analysis of an rct comparing two gic brands |
| topic | Atraumatic Restorative Treatment Glass ionomer cement Clinical trial Cost-effectiveness Restoration survival percentage Primary teeth Pediatric dentistry |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572022000100441&tlng=en |
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