Regulatory Functions and Mechanisms of Circular RNAs in Hepatic Stellate Cell Activation and Liver Fibrosis

Regulatory Functions and Mechanisms of Circular RNAs in Hepatic Stellate Cell Activation and Liver Fibrosis

Chronic liver injury induces the activation of hepatic stellate cells (HSCs) into myofibroblasts, which produce excessive amounts of extracellular matrix (ECM), resulting in tissue fibrosis. If the injury persists, these fibrous scars could be permanent and disrupt liver architecture and function. C...

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Bibliographic Details
Main Authors: Archittapon Nokkeaw, Pannathon Thamjamrassri, Pisit Tangkijvanich, Chaiyaboot Ariyachet
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cells
Subjects:
non-coding RNA
circular RNA
microRNA
hepatic stellate cells
liver fibrosis
Online Access:https://www.mdpi.com/2073-4409/12/3/378

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