Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literature
Primary leiomyomas are rare benign tumors of the lung and only 25 cases have been documented in children, most of which are endobronchial. Leiomyomas are benign smooth muscle neoplasms, usually diagnosed on morphological characteristics. However, immunohistochemistry plays a crucial role in the line...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2016-01-01
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| Series: | Indian Journal of Pathology and Microbiology |
| Subjects: | |
| Online Access: | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=87;epage=89;aulast=Awasthi |
| _version_ | 1818483290914422784 |
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| author | Ashutosh Awasthi Suparna Dubey Abha K Sabhikhi Sabyasachi Bal |
| author_facet | Ashutosh Awasthi Suparna Dubey Abha K Sabhikhi Sabyasachi Bal |
| author_sort | Ashutosh Awasthi |
| collection | DOAJ |
| description | Primary leiomyomas are rare benign tumors of the lung and only 25 cases have been documented in children, most of which are endobronchial. Leiomyomas are benign smooth muscle neoplasms, usually diagnosed on morphological characteristics. However, immunohistochemistry plays a crucial role in the lineage differentiation when these are encountered at unusual sites or with unexpected morphological features. We report a case of endobronchial tumor of a 13-year-old male child who presented with a dry cough and hemoptysis. A mass lesion in the right main bronchus was detected by bronchoscopy and contrast-enhanced computed tomography. On histopathological examination of the resected specimen, a diagnosis of myxoid leiomyoma was made. To the best of our knowledge, this is the first case of myxoid leiomyoma to be reported in the respiratory tract. This case also demonstrates the need for a high index of suspicion and the role of immunomarkers in the diagnosis of such challenging cases. |
| first_indexed | 2024-12-10T11:58:20Z |
| format | Article |
| id | doaj.art-f324e9405f2b45388cc8c34b2d43838d |
| institution | Directory Open Access Journal |
| issn | 0377-4929 |
| language | English |
| last_indexed | 2024-12-10T11:58:20Z |
| publishDate | 2016-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Pathology and Microbiology |
| spelling | doaj.art-f324e9405f2b45388cc8c34b2d43838d2022-12-22T01:49:42ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49292016-01-01591878910.4103/0377-4929.174830Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literatureAshutosh AwasthiSuparna DubeyAbha K SabhikhiSabyasachi BalPrimary leiomyomas are rare benign tumors of the lung and only 25 cases have been documented in children, most of which are endobronchial. Leiomyomas are benign smooth muscle neoplasms, usually diagnosed on morphological characteristics. However, immunohistochemistry plays a crucial role in the lineage differentiation when these are encountered at unusual sites or with unexpected morphological features. We report a case of endobronchial tumor of a 13-year-old male child who presented with a dry cough and hemoptysis. A mass lesion in the right main bronchus was detected by bronchoscopy and contrast-enhanced computed tomography. On histopathological examination of the resected specimen, a diagnosis of myxoid leiomyoma was made. To the best of our knowledge, this is the first case of myxoid leiomyoma to be reported in the respiratory tract. This case also demonstrates the need for a high index of suspicion and the role of immunomarkers in the diagnosis of such challenging cases.http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=87;epage=89;aulast=AwasthiEndobronchialimmunohistochemistryleiomyomamyxoid |
| spellingShingle | Ashutosh Awasthi Suparna Dubey Abha K Sabhikhi Sabyasachi Bal Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literature Indian Journal of Pathology and Microbiology Endobronchial immunohistochemistry leiomyoma myxoid |
| title | Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literature |
| title_full | Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literature |
| title_fullStr | Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literature |
| title_full_unstemmed | Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literature |
| title_short | Primary endobronchial myxoid leiomyoma in a child: An unusual case report and review of literature |
| title_sort | primary endobronchial myxoid leiomyoma in a child an unusual case report and review of literature |
| topic | Endobronchial immunohistochemistry leiomyoma myxoid |
| url | http://www.ijpmonline.org/article.asp?issn=0377-4929;year=2016;volume=59;issue=1;spage=87;epage=89;aulast=Awasthi |
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