Renal Cell Carcinoma-Infiltrating CD3<sup>low</sup> Vγ9Vδ1 T Cells Represent Potentially Novel Anti-Tumor Immune Players

Renal Cell Carcinoma-Infiltrating CD3<sup>low</sup> Vγ9Vδ1 T Cells Represent Potentially Novel Anti-Tumor Immune Players

Due to the highly immunogenic nature of renal cell carcinoma (RCC), the tumor microenvironment (TME) is enriched with various innate and adaptive immune subsets. In particular, gamma-delta (γδ) T cells can act as potent attractive mediators of adoptive cell transfer immunotherapy because of their un...

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Bibliographic Details
Main Authors: Hye Won Lee, Chanho Park, Je-Gun Joung, Minyong Kang, Yun Shin Chung, Won Joon Oh, Seon-Yong Yeom, Woong-Yang Park, Tae Jin Kim, Seong Il Seo
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Current Issues in Molecular Biology
Subjects:
renal cell carcinoma
tumor microenvironment
tumor-infiltrating lymphocytes
gamma-delta T cells
anti-tumor immunity
adoptive immunotherapy
Online Access:https://www.mdpi.com/1467-3045/43/1/19

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