YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes

YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes

Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that modulate innate immune responses and play essential roles in the pathogenesis of heart diseases. Although important, the molecular mechanisms controlling cardiac TLR genes expression have not been clearly addressed....

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Bibliographic Details
Main Authors: Yunan Gao, Yan Sun, Adife Gulhan Ercan-Sencicek, Justin S. King, Brynn N. Akerberg, Qing Ma, Maria I. Kontaridis, William T. Pu, Zhiqiang Lin
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
YAP
TEAD1
Toll-like receptor
heart
TLR4
cardiomyocyte
Online Access:https://www.mdpi.com/1422-0067/22/13/6649

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