A Novel Lipopolysaccharide Recognition Mechanism Mediated by Internalization in Teleost Macrophages

A Novel Lipopolysaccharide Recognition Mechanism Mediated by Internalization in Teleost Macrophages

Macrophages in teleosts are less sensitive to lipopolysaccharide (LPS) compared to mammals. The functional equivalent of the mammalian LPS surface receptor in teleost macrophages for the pro-inflammatory response is either non-existent or replaced by negative regulation. LPS signaling in teleost mac...

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Bibliographic Details
Main Authors: Xin-Jiang Lu, Ying-Jun Ning, He Liu, Li Nie, Jiong Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
teleost
macrophages
lipopolysaccharide
scavenger receptor class B2
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02758/full

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