Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China
PRRS virus (PRRSV) has undergone rapid evolution and resulted in immense economic losses worldwide. In the present study, a PRRSV strain named FJ0908 causing high abortion rate (25%) and mortality (40%) was detected in a swine herd in China. To determine if a new PRRSV genotype had emerged, we chara...
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| Format: | Article |
| Language: | English |
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PeerJ Inc.
2019-10-01
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| Series: | PeerJ |
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| Online Access: | https://peerj.com/articles/7859.pdf |
| _version_ | 1797419956497809408 |
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| author | Jiankui Liu Chunhua Wei Zhifeng Lin Wei Xia Ying Ma Ailing Dai Xiaoyan Yang |
| author_facet | Jiankui Liu Chunhua Wei Zhifeng Lin Wei Xia Ying Ma Ailing Dai Xiaoyan Yang |
| author_sort | Jiankui Liu |
| collection | DOAJ |
| description | PRRS virus (PRRSV) has undergone rapid evolution and resulted in immense economic losses worldwide. In the present study, a PRRSV strain named FJ0908 causing high abortion rate (25%) and mortality (40%) was detected in a swine herd in China. To determine if a new PRRSV genotype had emerged, we characterized the genetic characteristics of FJ0908. Phylogenetic analysis indicated that FJ0908 was related to 1-7-4-like strains circulating in the United States since 2014. Furthermore, the ORF5 sequence restriction fragment length polymorphism (RFLP) pattern of FJ0908 was 1-7-4. Additionally, FJ0908 had a 100 aa deletion (aa329–428) within nsp2, as compared to VR-2332, and the deletion pattern was consistent with most of 1-7-4 PRRSVs. Collectively, the data of this study contribute to the understanding of 1-7-4-like PRRSV molecular epidemiology in China. |
| first_indexed | 2024-03-09T06:55:39Z |
| format | Article |
| id | doaj.art-f3312f5e313e4488bde8a80025849ffc |
| institution | Directory Open Access Journal |
| issn | 2167-8359 |
| language | English |
| last_indexed | 2024-03-09T06:55:39Z |
| publishDate | 2019-10-01 |
| publisher | PeerJ Inc. |
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| spelling | doaj.art-f3312f5e313e4488bde8a80025849ffc2023-12-03T10:07:27ZengPeerJ Inc.PeerJ2167-83592019-10-017e785910.7717/peerj.7859Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, ChinaJiankui Liu0Chunhua Wei1Zhifeng Lin2Wei Xia3Ying Ma4Ailing Dai5Xiaoyan Yang6College of Life Sciences, Longyan University, Longyan, ChinaCollege of Life Sciences, Longyan University, Longyan, ChinaCollege of Animal Science, Fujian Agriculture and Forestry University, Fuzhou, ChinaCollege of Life Sciences, Longyan University, Longyan, ChinaCollege of Life Sciences, Longyan University, Longyan, ChinaCollege of Life Sciences, Longyan University, Longyan, ChinaCollege of Life Sciences, Longyan University, Longyan, ChinaPRRS virus (PRRSV) has undergone rapid evolution and resulted in immense economic losses worldwide. In the present study, a PRRSV strain named FJ0908 causing high abortion rate (25%) and mortality (40%) was detected in a swine herd in China. To determine if a new PRRSV genotype had emerged, we characterized the genetic characteristics of FJ0908. Phylogenetic analysis indicated that FJ0908 was related to 1-7-4-like strains circulating in the United States since 2014. Furthermore, the ORF5 sequence restriction fragment length polymorphism (RFLP) pattern of FJ0908 was 1-7-4. Additionally, FJ0908 had a 100 aa deletion (aa329–428) within nsp2, as compared to VR-2332, and the deletion pattern was consistent with most of 1-7-4 PRRSVs. Collectively, the data of this study contribute to the understanding of 1-7-4-like PRRSV molecular epidemiology in China.https://peerj.com/articles/7859.pdfPRRSVGenome sequence1-7-4Molecular characteristic |
| spellingShingle | Jiankui Liu Chunhua Wei Zhifeng Lin Wei Xia Ying Ma Ailing Dai Xiaoyan Yang Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China PeerJ PRRSV Genome sequence 1-7-4 Molecular characteristic |
| title | Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China |
| title_full | Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China |
| title_fullStr | Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China |
| title_full_unstemmed | Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China |
| title_short | Full genome sequence analysis of a 1-7-4-like PRRSV strain in Fujian Province, China |
| title_sort | full genome sequence analysis of a 1 7 4 like prrsv strain in fujian province china |
| topic | PRRSV Genome sequence 1-7-4 Molecular characteristic |
| url | https://peerj.com/articles/7859.pdf |
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