HIV-1 Packaging Visualised by In-Gel SHAPE

HIV-1 Packaging Visualised by In-Gel SHAPE

HIV-1 packages two copies of its gRNA into virions via an interaction with the viral structural protein Gag. Both copies and their native RNA structure are essential for virion infectivity. The precise stepwise nature of the packaging process has not been resolved. This is largely due to a prior lac...

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Bibliographic Details
Main Authors: Aaron R. D’Souza, Dhivya Jayaraman, Ziqi Long, Jingwei Zeng, Liam J. Prestwood, Charlene Chan, Dennis Kappei, Andrew M. L. Lever, Julia C. Kenyon
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Viruses
Subjects:
HIV-1
packaging
in-gel SHAPE
Gag
NC
RNA structure
Online Access:https://www.mdpi.com/1999-4915/13/12/2389

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