P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERU
Introduction: Liver abscesses are a rare and serious complication in liver transplantation associated with hepatic artery thrombosis, biliary stenosis, choledocho-jejunostomy, cholangitis, living donor liver transplantation, Split liver, DCD, liver biopsy and diabetes. Objectives: To show the experi...
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-09-01
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| Series: | Annals of Hepatology |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1665268121001745 |
| _version_ | 1819292955734704128 |
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| author | Augudberto Montufar Carlos Rondón Bacilio Wilmer Omar Mantilla José Rivera Alfonso Solar Bertha Cárdenas Carmen Cerrón Saul Espinoza Martin Padilla |
| author_facet | Augudberto Montufar Carlos Rondón Bacilio Wilmer Omar Mantilla José Rivera Alfonso Solar Bertha Cárdenas Carmen Cerrón Saul Espinoza Martin Padilla |
| author_sort | Augudberto Montufar |
| collection | DOAJ |
| description | Introduction: Liver abscesses are a rare and serious complication in liver transplantation associated with hepatic artery thrombosis, biliary stenosis, choledocho-jejunostomy, cholangitis, living donor liver transplantation, Split liver, DCD, liver biopsy and diabetes. Objectives: To show the experience in the diagnosis, treatment, and results of liver abscesses in liver transplant patients in 20 years in the Transplant Department of the Guillermo Almenara National Hospital. EsSalud. Methods: Descriptive, cross-sectional, retrospective study. We reviewed the demographic data and the clinical characteristics, type of graft, donor, time of transplantation, size, and number of lesions, as well as isolated germs, use of antimicrobials, treatment, and mortality. Results: Twelve patients were identified in 303 liver transplants (3.96%). The average age was 57 years. Symptoms: fever, pain, general malaise. Abnormal liver function test: 50% and 90% had elevated GGTP. Acute kidney injury in 6 cases (50%). Hospital staying: 32 days (4-135). Liver abscess developed at 63 months on average. Size 8 cm (2-23 cm). One lesion: 9 (75%); the most compromised liver segment was VI and VIII: Choledocho-jejunostomy: 83%. Biliary strictures (5 cases 41.6%): 2 related to hepatic artery thrombosis, 2 hepatic artery stenosis, and one case related to TACE. Treatment: Cultures: E. Coli and candida. Antibiotics:: Carbapenem and vancomycin. Surgical drainage (1, 8.3%) and percutaneous drains (11, 91.6%) were performed. Mortality was 8.3% (1 case: related to the abscess) Conclusions: The results of our experience show a similar prevalence to other studies, we found no relationship with the indication for transplantation, 80% of the cases occurred in the first 100 days, the main risk factors were biliodigestive diversion, vascular and biliary complications; Most of the treatment was by percutaneous drainage and antibiotic treatment lasted 4 to 6 weeks. |
| first_indexed | 2024-12-24T04:02:45Z |
| format | Article |
| id | doaj.art-f335823c7bac4707aa3a2df99a7218a6 |
| institution | Directory Open Access Journal |
| issn | 1665-2681 |
| language | English |
| last_indexed | 2024-12-24T04:02:45Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Annals of Hepatology |
| spelling | doaj.art-f335823c7bac4707aa3a2df99a7218a62022-12-21T17:16:17ZengElsevierAnnals of Hepatology1665-26812021-09-0124100475P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERUAugudberto Montufar0Carlos Rondón1Bacilio Wilmer2Omar Mantilla3José Rivera4Alfonso Solar5Bertha Cárdenas6Carmen Cerrón7Saul Espinoza8Martin Padilla9Departamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Medicina, Universidad Nacional Mayor de San Marcos, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, PerúDepartamento de Trasplantes Hospital Nacional Guillermo Almenara, Lima, Perú; Departamento de Medicina, Universidad Nacional Mayor de San Marcos, Lima, PerúIntroduction: Liver abscesses are a rare and serious complication in liver transplantation associated with hepatic artery thrombosis, biliary stenosis, choledocho-jejunostomy, cholangitis, living donor liver transplantation, Split liver, DCD, liver biopsy and diabetes. Objectives: To show the experience in the diagnosis, treatment, and results of liver abscesses in liver transplant patients in 20 years in the Transplant Department of the Guillermo Almenara National Hospital. EsSalud. Methods: Descriptive, cross-sectional, retrospective study. We reviewed the demographic data and the clinical characteristics, type of graft, donor, time of transplantation, size, and number of lesions, as well as isolated germs, use of antimicrobials, treatment, and mortality. Results: Twelve patients were identified in 303 liver transplants (3.96%). The average age was 57 years. Symptoms: fever, pain, general malaise. Abnormal liver function test: 50% and 90% had elevated GGTP. Acute kidney injury in 6 cases (50%). Hospital staying: 32 days (4-135). Liver abscess developed at 63 months on average. Size 8 cm (2-23 cm). One lesion: 9 (75%); the most compromised liver segment was VI and VIII: Choledocho-jejunostomy: 83%. Biliary strictures (5 cases 41.6%): 2 related to hepatic artery thrombosis, 2 hepatic artery stenosis, and one case related to TACE. Treatment: Cultures: E. Coli and candida. Antibiotics:: Carbapenem and vancomycin. Surgical drainage (1, 8.3%) and percutaneous drains (11, 91.6%) were performed. Mortality was 8.3% (1 case: related to the abscess) Conclusions: The results of our experience show a similar prevalence to other studies, we found no relationship with the indication for transplantation, 80% of the cases occurred in the first 100 days, the main risk factors were biliodigestive diversion, vascular and biliary complications; Most of the treatment was by percutaneous drainage and antibiotic treatment lasted 4 to 6 weeks.http://www.sciencedirect.com/science/article/pii/S1665268121001745 |
| spellingShingle | Augudberto Montufar Carlos Rondón Bacilio Wilmer Omar Mantilla José Rivera Alfonso Solar Bertha Cárdenas Carmen Cerrón Saul Espinoza Martin Padilla P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERU Annals of Hepatology |
| title | P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERU |
| title_full | P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERU |
| title_fullStr | P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERU |
| title_full_unstemmed | P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERU |
| title_short | P-115 MANAGEMENT AND OUTCOME OF LIVER ABCESS AFTER LIVER TRANSPLANTATION: EXPERIENCE OF A SINGLE CENTER IN PERU |
| title_sort | p 115 management and outcome of liver abcess after liver transplantation experience of a single center in peru |
| url | http://www.sciencedirect.com/science/article/pii/S1665268121001745 |
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