Drug-Induced Aseptic Meningitis Following Spinal Anesthesia

Meningitis is a very uncommon complication of spinal anesthesia, and drug-induced aseptic meningitis (DIAM) is even rarer. We present two cases of DIAM following spinal anesthesia with bupivacaine and ropivacaine, respectively. The patients presented shortly after the procedure with typical meningit...

Full description

Bibliographic Details
Main Authors: Ricardo Paquete Oliveira, Mafalda Teixeira, Sofia Cochito, Ana Furtado, Bruno Grima, José Delgado Alves
Format: Article
Language:English
Published: SMC MEDIA SRL 2019-12-01
Series:European Journal of Case Reports in Internal Medicine
Subjects:
Online Access:https://www.ejcrim.com/index.php/EJCRIM/article/view/1334
_version_ 1819265885732339712
author Ricardo Paquete Oliveira
Mafalda Teixeira
Sofia Cochito
Ana Furtado
Bruno Grima
José Delgado Alves
author_facet Ricardo Paquete Oliveira
Mafalda Teixeira
Sofia Cochito
Ana Furtado
Bruno Grima
José Delgado Alves
author_sort Ricardo Paquete Oliveira
collection DOAJ
description Meningitis is a very uncommon complication of spinal anesthesia, and drug-induced aseptic meningitis (DIAM) is even rarer. We present two cases of DIAM following spinal anesthesia with bupivacaine and ropivacaine, respectively. The patients presented shortly after the procedure with typical meningitis symptoms. Since CSF (cerebrospinal fluid) analysis could not initially exclude bacterial meningitis, they were started on empirical antibiotics. CSF was subsequently found to be negative for viruses and bacteria in both cases, and antibiotics were promptly stopped. Both patients improved rapidly and without neurological sequelae. While it remains a diagnosis of exclusion, it is important to be aware of DIAM as recognition of the condition can lead to shorter admission times and avoid unnecessary use of antibiotics.
first_indexed 2024-12-23T20:52:29Z
format Article
id doaj.art-f338d92bbade4678be73f52c54231e26
institution Directory Open Access Journal
issn 2284-2594
language English
last_indexed 2024-12-23T20:52:29Z
publishDate 2019-12-01
publisher SMC MEDIA SRL
record_format Article
series European Journal of Case Reports in Internal Medicine
spelling doaj.art-f338d92bbade4678be73f52c54231e262022-12-21T17:31:37ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942019-12-0110.12890/2019_0013341334Drug-Induced Aseptic Meningitis Following Spinal AnesthesiaRicardo Paquete Oliveira0Mafalda Teixeira1Sofia Cochito2Ana Furtado3Bruno Grima4José Delgado Alves5Serviço de Medicina IV, Hospital Prof. Doutor Fernando Fonseca, Amadora, PortugalServiço de Medicina IV, Hospital Prof. Doutor Fernando Fonseca, Amadora, PortugalDepartamento de Pediatria, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, EPE Clínica Universitária de Pediatria, Faculdade de Medicina, Universidade de Lisboa. Lisboa, PortugalServiço de Medicina IV, Hospital Prof. Doutor Fernando Fonseca, Amadora, PortugalServiço de Medicina IV, Hospital Prof. Doutor Fernando Fonseca, Amadora, PortugalServiço de Medicina IV, Hospital Prof. Doutor Fernando Fonseca, Amadora, PortugalMeningitis is a very uncommon complication of spinal anesthesia, and drug-induced aseptic meningitis (DIAM) is even rarer. We present two cases of DIAM following spinal anesthesia with bupivacaine and ropivacaine, respectively. The patients presented shortly after the procedure with typical meningitis symptoms. Since CSF (cerebrospinal fluid) analysis could not initially exclude bacterial meningitis, they were started on empirical antibiotics. CSF was subsequently found to be negative for viruses and bacteria in both cases, and antibiotics were promptly stopped. Both patients improved rapidly and without neurological sequelae. While it remains a diagnosis of exclusion, it is important to be aware of DIAM as recognition of the condition can lead to shorter admission times and avoid unnecessary use of antibiotics.https://www.ejcrim.com/index.php/EJCRIM/article/view/1334aseptic meningitisdrug-induced aseptic meningitisropivacainebupivacaine
spellingShingle Ricardo Paquete Oliveira
Mafalda Teixeira
Sofia Cochito
Ana Furtado
Bruno Grima
José Delgado Alves
Drug-Induced Aseptic Meningitis Following Spinal Anesthesia
European Journal of Case Reports in Internal Medicine
aseptic meningitis
drug-induced aseptic meningitis
ropivacaine
bupivacaine
title Drug-Induced Aseptic Meningitis Following Spinal Anesthesia
title_full Drug-Induced Aseptic Meningitis Following Spinal Anesthesia
title_fullStr Drug-Induced Aseptic Meningitis Following Spinal Anesthesia
title_full_unstemmed Drug-Induced Aseptic Meningitis Following Spinal Anesthesia
title_short Drug-Induced Aseptic Meningitis Following Spinal Anesthesia
title_sort drug induced aseptic meningitis following spinal anesthesia
topic aseptic meningitis
drug-induced aseptic meningitis
ropivacaine
bupivacaine
url https://www.ejcrim.com/index.php/EJCRIM/article/view/1334
work_keys_str_mv AT ricardopaqueteoliveira druginducedasepticmeningitisfollowingspinalanesthesia
AT mafaldateixeira druginducedasepticmeningitisfollowingspinalanesthesia
AT sofiacochito druginducedasepticmeningitisfollowingspinalanesthesia
AT anafurtado druginducedasepticmeningitisfollowingspinalanesthesia
AT brunogrima druginducedasepticmeningitisfollowingspinalanesthesia
AT josedelgadoalves druginducedasepticmeningitisfollowingspinalanesthesia