Generation of three-dimensional meat-like tissue from stable pig epiblast stem cells

Generation of three-dimensional meat-like tissue from stable pig epiblast stem cells

Abstract Cultured meat production has emerged as a breakthrough technology for the global food industry with the potential to reduce challenges associated with environmental sustainability, global public health, animal welfare, and competition for food between humans and animals. The muscle stem cel...

Full description

Bibliographic Details
Main Authors:	Gaoxiang Zhu, Dengfeng Gao, Linzi Li, Yixuan Yao, Yingjie Wang, Minglei Zhi, Jinying Zhang, Xinze Chen, Qianqian Zhu, Jie Gao, Tianzhi Chen, Xiaowei Zhang, Tong Wang, Suying Cao, Aijin Ma, Xianchao Feng, Jianyong Han
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-12-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-023-44001-8

Similar Items

Pluripotent stem cells secrete Activin A to improve their epiblast competency after injection into recipient embryos
by: Jinzhu Xiang, et al.
Published: (2017-10-01)

Epiblast ground state is controlled by canonical Wnt/β-catenin signaling in the postimplantation mouse embryo and epiblast stem cells.
by: Tomoyuki Sumi, et al.
Published: (2013-01-01)

A cytokine screen using CRISPR-Cas9 knock-in reporter pig iPS cells reveals that Activin A regulates NANOG
by: Junjun Xu, et al.
Published: (2020-02-01)

Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells.
by: Le Tran Phuc Khoa, et al.
Published: (2016-01-01)

ERK inhibition promotes neuroectodermal precursor commitment by blocking self-renewal and primitive streak formation of the epiblast
by: Yang Yu, et al.
Published: (2018-01-01)

Movement of AVE and epiblast cells during pre-gastrulation mouse embryogenesis
by: Srinivas, S, et al.
Published: (2005)

An in vitro stem cell model of human epiblast and yolk sac interaction
by: Kirsty ML Mackinlay, et al.
Published: (2021-08-01)

NANOG initiates epiblast fate through the coordination of pluripotency genes expression
by: Nicolas Allègre, et al.
Published: (2022-06-01)

AMPK activation reverts mouse epiblast stem cells to naive state
by: Yajing Liu, et al.
Published: (2021-07-01)

Embryonic Cul4b is important for epiblast growth and location of primitive streak layer cells.
by: Chun-Yu Chen, et al.
Published: (2019-01-01)

IRF-1 expressed in the inner cell mass of the porcine early blastocyst enhances the pluripotency of induced pluripotent stem cells
by: Bingbo Shi, et al.
Published: (2020-11-01)

DISTRIBUTION OF PRIMITIVE ENDODERM AND EPIBLAST LINEAGE SPECIFIC FACTORS IN LATE STAGE BLASTOCYSTS
by: Duygu Mutluay
Published: (2016-12-01)

Functional Characterization of Endothelial Cells Differentiated from Porcine Epiblast Stem Cells
by: Joon-Hong Shin, et al.
Published: (2022-05-01)

Successful Reprogramming of Epiblast Stem Cells by Blocking Nuclear Localization of β-Catenin
by: Hideyuki Murayama, et al.
Published: (2015-01-01)

E-cadherin promotes incorporation of mouse epiblast stem cells into normal development.
by: Satoshi Ohtsuka, et al.
Published: (2012-01-01)

In Vivo Differentiation Potential of Epiblast Stem Cells Revealed by Chimeric Embryo Formation
by: Yali Huang, et al.
Published: (2012-12-01)

The epigenetic modifier Fam208a is required to maintain epiblast cell fitness
by: Shohag Bhargava, et al.
Published: (2017-08-01)

BET proteins are essential for the specification and maintenance of the epiblast lineage in mouse preimplantation embryos
by: Mami Tsume-Kajioka, et al.
Published: (2022-03-01)

Epiblastic Cited2 deficiency results in cardiac phenotypic heterogeneity and provides a mechanism for haploinsufficiency.
by: MacDonald, S, et al.
Published: (2008)

Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling
by: Xin Huang, et al.
Published: (2017-11-01)

Five Transcription Factors and FGF Pathway Inhibition Efficiently Induce Erythroid Differentiation in the Epiblast
by: Wei Weng, et al.
Published: (2014-03-01)

Neural stem cells derived from epiblast stem cells display distinctive properties
by: Hyo Jin Jang, et al.
Published: (2014-03-01)

Aberrant H3K4me3 modification of epiblast genes of extraembryonic tissue causes placental defects and implantation failure in mouse IVF embryos
by: Dandan Bai, et al.
Published: (2022-05-01)

Live imaging of whole mouse embryos during gastrulation: migration analyses of epiblast and mesodermal cells.
by: Takehiko Ichikawa, et al.
Published: (2013-01-01)

Molecular profiling of the basement membrane of pluripotent epiblast cells in post-implantation stage mouse embryos
by: Sugiko Futaki, et al.
Published: (2019-12-01)

A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells.
by: Masahide Seki, et al.
Published: (2014-01-01)

Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency
by: Alessandro Fiorenzano, et al.
Published: (2016-09-01)

New cell lines from mouse epiblast share defining features with human embryonic stem cells.
by: Tesar, P, et al.
Published: (2007)

Epiblastic Cited2 function explains pleiotropy and penetrance of cardiac malformation resulting from its deficiency
by: Macdonald, S, et al.
Published: (2007)

A Simple and Robust Method for Establishing Homogeneous Mouse Epiblast Stem Cell Lines by Wnt Inhibition
by: Michihiko Sugimoto, et al.
Published: (2015-04-01)

Epiblast-like stem cells established by Wnt/β-catenin signaling manifest distinct features of formative pluripotency and germline competence
by: Qing Luo, et al.
Published: (2023-01-01)

Src-Yap1 signaling axis controls the trophectoderm and epiblast lineage differentiation in mouse embryonic stem cells
by: Juan Luo, et al.
Published: (2021-07-01)

Reprogramming of rabbit induced pluripotent stem cells toward epiblast and chimeric competency using Krüppel-like factors
by: Yann Tapponnier, et al.
Published: (2017-10-01)

Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells
by: Shaopeng Zhang, et al.
Published: (2019-01-01)

Col1α2-Cre-mediated recombination occurs in various cell types due to Cre expression in epiblasts
by: Yuzuru Matsumoto, et al.
Published: (2023-12-01)

Endogenous WNT Signals Mediate BMP-Induced and Spontaneous Differentiation of Epiblast Stem Cells and Human Embryonic Stem Cells
by: Dorota Kurek, et al.
Published: (2015-01-01)

Specific epiblast loss and hypoblast impairment in cattle embryos sensitized to survival signalling by ubiquitous overexpression of the proapoptotic gene BAD.
by: Jessica van Leeuwen, et al.
Published: (2014-01-01)

Testicular somatic cell-like cells derived from embryonic stem cells induce differentiation of epiblasts into germ cells
by: Holly Rore, et al.
Published: (2021-06-01)

Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways.
by: Ludovic Vallier, et al.
Published: (2009-06-01)

Effect of Cold Rolling and Annealing on the Microstructure and Texture of Erbium Metal
by: Shiying Chen, et al.
Published: (2022-02-01)