7-Ketocholesterol and cholestane-triol increase expression of SMO and LXRα signaling pathways in a human breast cancer cell line

7-Ketocholesterol and cholestane-triol increase expression of SMO and LXRα signaling pathways in a human breast cancer cell line

Oxysterols are 27-carbon oxidation products of cholesterol metabolism. Oxysterols possess several biological actions, including the promotion of cell death. Here, we examined the ability of 7-ketocholesterol (7-KC), cholestane-3β-5α-6β-triol (triol), and a mixture of 5α-cholestane-3β,6β-diol and 5α-...

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Bibliographic Details
Main Authors: Debora Levy, Thatiana Correa de Melo, Beatriz A. Oliveira, Jessica L. Paz, Fabio A. de Freitas, Cadiele O. Reichert, Alessandro Rodrigues, Sergio P. Bydlowski
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Biochemistry and Biophysics Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580818302772

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