Research Progress on Skin Aging and Active Ingredients
With the advancement of living standards in modern society and the emergence of an aging population, an increasing number of people are becoming interested in the topic of aging and anti-aging. An important feature of aging is skin aging, and women are particularly concerned about skin aging. In the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/14/5556 |
| _version_ | 1827732212791902208 |
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| author | Xin He Fang Wan Wenhui Su Weidong Xie |
| author_facet | Xin He Fang Wan Wenhui Su Weidong Xie |
| author_sort | Xin He |
| collection | DOAJ |
| description | With the advancement of living standards in modern society and the emergence of an aging population, an increasing number of people are becoming interested in the topic of aging and anti-aging. An important feature of aging is skin aging, and women are particularly concerned about skin aging. In the field of cosmetics, the market share of anti-aging products is increasing year by year. This article reviews the research and development progress of skin aging and related active compounds both domestically and internationally in recent years. The results show that, in terms of the research on skin aging, the popular theories mainly include free radicals and oxidative stress theory, inflammation theory, photoaging theory, and nonenzymatic glycosyl chemistry theory. In terms of research on the active ingredients with anti-aging activities in the skin, there are numerous reports on related products in clinical studies on human subjects, animal experiments, and experimental studies on cell cultures, with a variety of types. Most of the compounds against skin aging are sourced from natural products and their action mechanisms are mainly related to scavenging oxygen free radicals and enhancing antioxidant defenses. This review provides important references for the future research of skin aging and the development of related products. Although there is a great progress in skin aging including related active ingredients, ideal compounds or products are still lacking and need to be further validated. New mechanisms of skin aging, new active ingredients sourced from natural and artificial products, and new pharmaceutical forms including further clinical validations should be further investigated in the future. |
| first_indexed | 2024-03-11T00:47:27Z |
| format | Article |
| id | doaj.art-f33bb2035a4847dc9b961a1257fe9a59 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T00:47:27Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-f33bb2035a4847dc9b961a1257fe9a592023-11-18T20:43:50ZengMDPI AGMolecules1420-30492023-07-012814555610.3390/molecules28145556Research Progress on Skin Aging and Active IngredientsXin He0Fang Wan1Wenhui Su2Weidong Xie3State Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaState Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaState Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaState Key Laboratory of Chemical Oncogenomics, Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, ChinaWith the advancement of living standards in modern society and the emergence of an aging population, an increasing number of people are becoming interested in the topic of aging and anti-aging. An important feature of aging is skin aging, and women are particularly concerned about skin aging. In the field of cosmetics, the market share of anti-aging products is increasing year by year. This article reviews the research and development progress of skin aging and related active compounds both domestically and internationally in recent years. The results show that, in terms of the research on skin aging, the popular theories mainly include free radicals and oxidative stress theory, inflammation theory, photoaging theory, and nonenzymatic glycosyl chemistry theory. In terms of research on the active ingredients with anti-aging activities in the skin, there are numerous reports on related products in clinical studies on human subjects, animal experiments, and experimental studies on cell cultures, with a variety of types. Most of the compounds against skin aging are sourced from natural products and their action mechanisms are mainly related to scavenging oxygen free radicals and enhancing antioxidant defenses. This review provides important references for the future research of skin aging and the development of related products. Although there is a great progress in skin aging including related active ingredients, ideal compounds or products are still lacking and need to be further validated. New mechanisms of skin aging, new active ingredients sourced from natural and artificial products, and new pharmaceutical forms including further clinical validations should be further investigated in the future.https://www.mdpi.com/1420-3049/28/14/5556anti-aging ingredientsinflammationphotoagingreactive oxygen speciesskin aging |
| spellingShingle | Xin He Fang Wan Wenhui Su Weidong Xie Research Progress on Skin Aging and Active Ingredients Molecules anti-aging ingredients inflammation photoaging reactive oxygen species skin aging |
| title | Research Progress on Skin Aging and Active Ingredients |
| title_full | Research Progress on Skin Aging and Active Ingredients |
| title_fullStr | Research Progress on Skin Aging and Active Ingredients |
| title_full_unstemmed | Research Progress on Skin Aging and Active Ingredients |
| title_short | Research Progress on Skin Aging and Active Ingredients |
| title_sort | research progress on skin aging and active ingredients |
| topic | anti-aging ingredients inflammation photoaging reactive oxygen species skin aging |
| url | https://www.mdpi.com/1420-3049/28/14/5556 |
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