Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i>
Kisspeptins are neuropeptides encoded by the <i>kiss1</i> gene, and little is known about them outside the vertebrate lineage. Two kisspeptin-type neuropeptides (KPs) have been discovered in <i>Apostichopus japonicus</i> (AjK1 and AjK2), an edible sea cucumber, and have been...
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MDPI AG
2023-02-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/13/4/705 |
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| author | Xueying Guo Libin Zhang Kang Xiao |
| author_facet | Xueying Guo Libin Zhang Kang Xiao |
| author_sort | Xueying Guo |
| collection | DOAJ |
| description | Kisspeptins are neuropeptides encoded by the <i>kiss1</i> gene, and little is known about them outside the vertebrate lineage. Two kisspeptin-type neuropeptides (KPs) have been discovered in <i>Apostichopus japonicus</i> (AjK1 and AjK2), an edible sea cucumber, and have been linked to reproductive and metabolic regulation. In this study, we evaluated how KPs affected locomotor behavior in one control group and two treatment groups (AjK1 and AjK2). We discovered that AjK1 had a significant dose effect, primarily by shortening the stride length and duration of movement to reduce the sea cucumber movement distance, whereas AjK2 had little inhibitory effect at the same dose. The levels of phosphatidylethanolamine (PE), phosphatidylcholine (PC), uridine, glycine, and L-serine in the longitudinal muscle of <i>A. japonicus</i> treated with AjK1 differed significantly from those of the control, which may explain the observed changes in locomotor behavior. Treatment with AjK2 induced changes in aspartate levels. Our results imply that AjK1 is more likely than AjK2 to have a role in the regulation of <i>A. japonicus</i> locomotion. |
| first_indexed | 2024-03-11T09:16:31Z |
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| id | doaj.art-f33c3a7f34e544ee999efa8ce74f84c2 |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-11T09:16:31Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Animals |
| spelling | doaj.art-f33c3a7f34e544ee999efa8ce74f84c22023-11-16T18:40:25ZengMDPI AGAnimals2076-26152023-02-0113470510.3390/ani13040705Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i>Xueying Guo0Libin Zhang1Kang Xiao2CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, ChinaCAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, ChinaBeijing Yanshan Earth Critical Zone National Research Station, College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 101408, ChinaKisspeptins are neuropeptides encoded by the <i>kiss1</i> gene, and little is known about them outside the vertebrate lineage. Two kisspeptin-type neuropeptides (KPs) have been discovered in <i>Apostichopus japonicus</i> (AjK1 and AjK2), an edible sea cucumber, and have been linked to reproductive and metabolic regulation. In this study, we evaluated how KPs affected locomotor behavior in one control group and two treatment groups (AjK1 and AjK2). We discovered that AjK1 had a significant dose effect, primarily by shortening the stride length and duration of movement to reduce the sea cucumber movement distance, whereas AjK2 had little inhibitory effect at the same dose. The levels of phosphatidylethanolamine (PE), phosphatidylcholine (PC), uridine, glycine, and L-serine in the longitudinal muscle of <i>A. japonicus</i> treated with AjK1 differed significantly from those of the control, which may explain the observed changes in locomotor behavior. Treatment with AjK2 induced changes in aspartate levels. Our results imply that AjK1 is more likely than AjK2 to have a role in the regulation of <i>A. japonicus</i> locomotion.https://www.mdpi.com/2076-2615/13/4/705<i>Apostichopus japonicus</i>kisspeptin-type neuropeptidelocomotionlongitudinal musclemetabolic physiology |
| spellingShingle | Xueying Guo Libin Zhang Kang Xiao Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i> Animals <i>Apostichopus japonicus</i> kisspeptin-type neuropeptide locomotion longitudinal muscle metabolic physiology |
| title | Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i> |
| title_full | Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i> |
| title_fullStr | Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i> |
| title_full_unstemmed | Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i> |
| title_short | Effect of Kisspeptin-Type Neuropeptide on Locomotor Behavior and Muscle Physiology in the Sea Cucumber <i>Apostichopus japonicus</i> |
| title_sort | effect of kisspeptin type neuropeptide on locomotor behavior and muscle physiology in the sea cucumber i apostichopus japonicus i |
| topic | <i>Apostichopus japonicus</i> kisspeptin-type neuropeptide locomotion longitudinal muscle metabolic physiology |
| url | https://www.mdpi.com/2076-2615/13/4/705 |
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