Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of Ducks
Mutations in the <i>SOX10</i> gene affect the plumage color of chickens and pigeons. The mutation also causes abnormal pigmentation of the skin and hair color, as well as postnatal growth retardation and reproduction problems in humans and mice. In this study, we investigated the associa...
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| Format: | Article |
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MDPI AG
2022-11-01
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| Series: | Animals |
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| Online Access: | https://www.mdpi.com/2076-2615/12/23/3345 |
| _version_ | 1797463792131506176 |
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| author | Teysar Adi Sarjana Gongyan Zhang |
| author_facet | Teysar Adi Sarjana Gongyan Zhang |
| author_sort | Teysar Adi Sarjana |
| collection | DOAJ |
| description | Mutations in the <i>SOX10</i> gene affect the plumage color of chickens and pigeons. The mutation also causes abnormal pigmentation of the skin and hair color, as well as postnatal growth retardation and reproduction problems in humans and mice. In this study, we investigated the association between the <i>SOX10</i> gene and plumage color and reproductive traits of ducks using SNPs. We found six novel SNPs from 11 identified SNP sites using direct sequencing for PCR products from three different mixed DNA pools. We found two coding SNPs to be associated with the plumage color of ducks (ZJU1.0 Chr1. g.54065419C>T and g.54070844C>T), and found three coding SNPs associated with the reproductive traits of ducks (g.54065419C>T, g.54070844C>T, and g.54070904C>T), which were age at sexual maturity, body weight at sexual maturity, and the Haugh unit for egg quality traits and egg production in different productive periods. These results also indicated that the T alleles of the three SNPs of the coding region of <i>SOX10</i> contribute to lower reproductive traits. |
| first_indexed | 2024-03-09T17:55:45Z |
| format | Article |
| id | doaj.art-f33deaeabf144d9faad00002321e78ad |
| institution | Directory Open Access Journal |
| issn | 2076-2615 |
| language | English |
| last_indexed | 2024-03-09T17:55:45Z |
| publishDate | 2022-11-01 |
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| series | Animals |
| spelling | doaj.art-f33deaeabf144d9faad00002321e78ad2023-11-24T10:25:33ZengMDPI AGAnimals2076-26152022-11-011223334510.3390/ani12233345Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of DucksTeysar Adi Sarjana0Gongyan Zhang1Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaKey Laboratory of Agricultural Animal Genetics, Breeding and Reproduction, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, ChinaMutations in the <i>SOX10</i> gene affect the plumage color of chickens and pigeons. The mutation also causes abnormal pigmentation of the skin and hair color, as well as postnatal growth retardation and reproduction problems in humans and mice. In this study, we investigated the association between the <i>SOX10</i> gene and plumage color and reproductive traits of ducks using SNPs. We found six novel SNPs from 11 identified SNP sites using direct sequencing for PCR products from three different mixed DNA pools. We found two coding SNPs to be associated with the plumage color of ducks (ZJU1.0 Chr1. g.54065419C>T and g.54070844C>T), and found three coding SNPs associated with the reproductive traits of ducks (g.54065419C>T, g.54070844C>T, and g.54070904C>T), which were age at sexual maturity, body weight at sexual maturity, and the Haugh unit for egg quality traits and egg production in different productive periods. These results also indicated that the T alleles of the three SNPs of the coding region of <i>SOX10</i> contribute to lower reproductive traits.https://www.mdpi.com/2076-2615/12/23/3345single-nucleotide polymorphismsgene mutationgene sequencingegg traitsage at sexual maturityegg weight |
| spellingShingle | Teysar Adi Sarjana Gongyan Zhang Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of Ducks Animals single-nucleotide polymorphisms gene mutation gene sequencing egg traits age at sexual maturity egg weight |
| title | Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of Ducks |
| title_full | Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of Ducks |
| title_fullStr | Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of Ducks |
| title_full_unstemmed | Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of Ducks |
| title_short | Association between Synonymous SNPs of <i>SOX10</i> and Plumage Color and Reproductive Traits of Ducks |
| title_sort | association between synonymous snps of i sox10 i and plumage color and reproductive traits of ducks |
| topic | single-nucleotide polymorphisms gene mutation gene sequencing egg traits age at sexual maturity egg weight |
| url | https://www.mdpi.com/2076-2615/12/23/3345 |
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