Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial Infarction
Introduction: Myocardial infarction (MI) is the irreversible cell death caused by ischemia in parts of myocardium. Atrial and brain natriuretic peptides (ANP and BNP) are known as strong markers of myocardial infarction. This research aimed to evaluate the effect of precedent of six-week light inten...
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| Format: | Article |
| Language: | English |
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Islamic Azad University
2017-12-01
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| Series: | Report of Health Care |
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| Online Access: | http://jrhc.miau.ac.ir/article_2859_de839c1f4686bc70a5e78b5559d61382.pdf |
| _version_ | 1818880691445694464 |
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| author | Mehran Ghahramani Sara Karbalaeifar |
| author_facet | Mehran Ghahramani Sara Karbalaeifar |
| author_sort | Mehran Ghahramani |
| collection | DOAJ |
| description | Introduction: Myocardial infarction (MI) is the irreversible cell death caused by ischemia in parts of myocardium. Atrial and brain natriuretic peptides (ANP and BNP) are known as strong markers of myocardial infarction. This research aimed to evaluate the effect of precedent of six-week light intensity interval training (LIIT) on the ANP and BNP gene expression in rats after Myocardial Infarction. Method: Twelve Wistar male rats of 10 weeks old and mean weight 250-300gr were allocated in two groups with six Rats in each groups of 1. LIIT (60 minutes interval running on a treadmill, each cycle including four minutes of running with an intensity of 55-60% VO2max and two minutes of active recovery with a 45-50% VO2max intensity, three days a week for six weeks) and 2. control group (without any precedent of training). Real-time PCR was used to assess the expression of ANP and BNP genes in myocardium (after inducing MI By blocking left coronary artery by surgery). For statistical analysis of data independent sample t test (p≤0.05) was used. Results: Light intensity interval training has significant effect on decreasing the gene expression of ANP (p=0.01) and BNP (p=0.001) in rats after myocardial infarction. Conclusion: It appears that adaptation to light intensity interval training controls and moderates the secretion of cardiac hormones in rats after myocardial infarction. |
| first_indexed | 2024-12-19T14:50:00Z |
| format | Article |
| id | doaj.art-f33f0bfb445d49bf99685afdaecaf287 |
| institution | Directory Open Access Journal |
| issn | 2423-4141 2423-4141 |
| language | English |
| last_indexed | 2024-12-19T14:50:00Z |
| publishDate | 2017-12-01 |
| publisher | Islamic Azad University |
| record_format | Article |
| series | Report of Health Care |
| spelling | doaj.art-f33f0bfb445d49bf99685afdaecaf2872022-12-21T20:16:52ZengIslamic Azad UniversityReport of Health Care2423-41412423-41412017-12-013410162859Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial InfarctionMehran Ghahramani0Sara Karbalaeifar1Department of Physical Education, Gilan-E-Gharb, Islamic Azad University, Gilan-E-Gharb,Iran.Department of Physical Education, Tehran University, Kish International Campus, Kish, IranIntroduction: Myocardial infarction (MI) is the irreversible cell death caused by ischemia in parts of myocardium. Atrial and brain natriuretic peptides (ANP and BNP) are known as strong markers of myocardial infarction. This research aimed to evaluate the effect of precedent of six-week light intensity interval training (LIIT) on the ANP and BNP gene expression in rats after Myocardial Infarction. Method: Twelve Wistar male rats of 10 weeks old and mean weight 250-300gr were allocated in two groups with six Rats in each groups of 1. LIIT (60 minutes interval running on a treadmill, each cycle including four minutes of running with an intensity of 55-60% VO2max and two minutes of active recovery with a 45-50% VO2max intensity, three days a week for six weeks) and 2. control group (without any precedent of training). Real-time PCR was used to assess the expression of ANP and BNP genes in myocardium (after inducing MI By blocking left coronary artery by surgery). For statistical analysis of data independent sample t test (p≤0.05) was used. Results: Light intensity interval training has significant effect on decreasing the gene expression of ANP (p=0.01) and BNP (p=0.001) in rats after myocardial infarction. Conclusion: It appears that adaptation to light intensity interval training controls and moderates the secretion of cardiac hormones in rats after myocardial infarction.http://jrhc.miau.ac.ir/article_2859_de839c1f4686bc70a5e78b5559d61382.pdfMyocardial InfarctionANPBNPLight Intensity Interval Training |
| spellingShingle | Mehran Ghahramani Sara Karbalaeifar Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial Infarction Report of Health Care Myocardial Infarction ANP BNP Light Intensity Interval Training |
| title | Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial Infarction |
| title_full | Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial Infarction |
| title_fullStr | Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial Infarction |
| title_full_unstemmed | Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial Infarction |
| title_short | Effect of Six Weeks Light Intensity Interval Training on ANP and BNP Gene Expression Levels after Myocardial Infarction |
| title_sort | effect of six weeks light intensity interval training on anp and bnp gene expression levels after myocardial infarction |
| topic | Myocardial Infarction ANP BNP Light Intensity Interval Training |
| url | http://jrhc.miau.ac.ir/article_2859_de839c1f4686bc70a5e78b5559d61382.pdf |
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