The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells.

The epidermal growth factor receptor (EGFR) promotes uptake of influenza A viruses (IAV) into host cells.

Influenza A viruses (IAV) bind to sialic-acids at cellular surfaces and enter cells by using endocytotic routes. There is evidence that this process does not occur constitutively but requires induction of specific cellular signals, including activation of PI3K that promotes virus internalization. Th...

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Bibliographic Details
Main Authors: Thorsten Eierhoff, Eike R Hrincius, Ursula Rescher, Stephan Ludwig, Christina Ehrhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20844577/?tool=EBI

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