Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center
Abstract Background There is a foreseeable trend that life expectancy is on the rise in many parts of the world. More and more patients will present with colorectal cancer at extreme old age and advanced age is a well-known risk factor for adverse outcomes after surgery. The aim of this study is to...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-10-01
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| Series: | BMC Surgery |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12893-019-0623-4 |
| _version_ | 1818126389159657472 |
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| author | Toi Yin Chan Chi Chung Foo Wai Lun Law Oswens Lo |
| author_facet | Toi Yin Chan Chi Chung Foo Wai Lun Law Oswens Lo |
| author_sort | Toi Yin Chan |
| collection | DOAJ |
| description | Abstract Background There is a foreseeable trend that life expectancy is on the rise in many parts of the world. More and more patients will present with colorectal cancer at extreme old age and advanced age is a well-known risk factor for adverse outcomes after surgery. The aim of this study is to evaluate the outcomes of colorectal cancer surgery in patients aged 90 or above. Method A retrospective analysis of consecutive patients aged 90 or above who underwent operations for colorectal cancer between January 1996 and December 2015 was performed. The primary outcomes were the complications rate, 30-day and 180-day mortality rates. Results A total of 57 patients were included in the analysis. The majority of them were women (64.9%). The median age was 92 years. Most of the surgery was of curative intent (77.2%), performed under elective setting (57.9%) and with open approach (78.9%). 36.8% of patients had postoperative complications, with pneumonia being the commonest. The 30-day and 180-day mortality rate was 7 and 31.6% respectively. History of ischemic heart disease and surgery under emergency setting were predictors of postoperative complications. Pneumonia, preoperative leukocytosis and Charlson comorbidity score ≥ 9 were predictors of 180-day mortality. The one and two-year survival rate for elective surgery was 69.7 and 54.5% respectively. Conclusion The outcomes of colorectal cancer surgery for nonagenarians could be favorable in a selected group of patients. Future study on better risk profiling and ways to improve outcomes is warranted. |
| first_indexed | 2024-12-11T07:00:41Z |
| format | Article |
| id | doaj.art-f341cc8813f84a2db19f29c9227cc193 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-12-11T07:00:41Z |
| publishDate | 2019-10-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-f341cc8813f84a2db19f29c9227cc1932022-12-22T01:16:37ZengBMCBMC Surgery1471-24822019-10-011911810.1186/s12893-019-0623-4Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary centerToi Yin Chan0Chi Chung Foo1Wai Lun Law2Oswens Lo3Department of Surgery, Queen Mary HospitalDepartment of Surgery, The University of Hong KongDepartment of Surgery, The University of Hong KongDepartment of Surgery, Queen Mary HospitalAbstract Background There is a foreseeable trend that life expectancy is on the rise in many parts of the world. More and more patients will present with colorectal cancer at extreme old age and advanced age is a well-known risk factor for adverse outcomes after surgery. The aim of this study is to evaluate the outcomes of colorectal cancer surgery in patients aged 90 or above. Method A retrospective analysis of consecutive patients aged 90 or above who underwent operations for colorectal cancer between January 1996 and December 2015 was performed. The primary outcomes were the complications rate, 30-day and 180-day mortality rates. Results A total of 57 patients were included in the analysis. The majority of them were women (64.9%). The median age was 92 years. Most of the surgery was of curative intent (77.2%), performed under elective setting (57.9%) and with open approach (78.9%). 36.8% of patients had postoperative complications, with pneumonia being the commonest. The 30-day and 180-day mortality rate was 7 and 31.6% respectively. History of ischemic heart disease and surgery under emergency setting were predictors of postoperative complications. Pneumonia, preoperative leukocytosis and Charlson comorbidity score ≥ 9 were predictors of 180-day mortality. The one and two-year survival rate for elective surgery was 69.7 and 54.5% respectively. Conclusion The outcomes of colorectal cancer surgery for nonagenarians could be favorable in a selected group of patients. Future study on better risk profiling and ways to improve outcomes is warranted.http://link.springer.com/article/10.1186/s12893-019-0623-4NonagenarianColorectal cancerElderly |
| spellingShingle | Toi Yin Chan Chi Chung Foo Wai Lun Law Oswens Lo Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center BMC Surgery Nonagenarian Colorectal cancer Elderly |
| title | Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center |
| title_full | Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center |
| title_fullStr | Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center |
| title_full_unstemmed | Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center |
| title_short | Outcomes of colorectal cancer surgery in the nonagenarians: 20-year result from a tertiary center |
| title_sort | outcomes of colorectal cancer surgery in the nonagenarians 20 year result from a tertiary center |
| topic | Nonagenarian Colorectal cancer Elderly |
| url | http://link.springer.com/article/10.1186/s12893-019-0623-4 |
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