Atorvastatin mitigates cyclophosphamide-induced hepatotoxicity via suppression of oxidative stress and apoptosis in rat model

Cyclophosphamide (CP), as a chemotherapy drug, induces hepatotoxicity through causing oxidative stress. Atorvastatin (ATV) at a low dose has antioxidant and anti-inflammatory properties. The present study was designed to investigate the protective effects of ATV against CP-induced hepatotoxicity in...

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Bibliografski detalji
Glavni autori: Maedeh Hamzeh, Seyed Jalal Hosseinimehr, Ali Reza Khalatbary, Hamid Reza Mohammadi, Ayat Dashti, Fereshteh Talebpour Amiri
Format: Članak
Jezik:English
Izdano: Wolters Kluwer Medknow Publications 2018-01-01
Serija:Research in Pharmaceutical Sciences
Teme:
Online pristup:http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2018;volume=13;issue=5;spage=440;epage=449;aulast=Hamzeh