Atorvastatin mitigates cyclophosphamide-induced hepatotoxicity via suppression of oxidative stress and apoptosis in rat model
Cyclophosphamide (CP), as a chemotherapy drug, induces hepatotoxicity through causing oxidative stress. Atorvastatin (ATV) at a low dose has antioxidant and anti-inflammatory properties. The present study was designed to investigate the protective effects of ATV against CP-induced hepatotoxicity in...
Glavni autori: | , , , , , |
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Format: | Članak |
Jezik: | English |
Izdano: |
Wolters Kluwer Medknow Publications
2018-01-01
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Serija: | Research in Pharmaceutical Sciences |
Teme: | |
Online pristup: | http://www.rpsjournal.net/article.asp?issn=1735-5362;year=2018;volume=13;issue=5;spage=440;epage=449;aulast=Hamzeh |