T Cell Repertoire Diversity Is Decreased in Type 1 Diabetes Patients
Type 1 diabetes mellitus (T1D) is an immune-mediated disease. The autoreactive T cells in T1D patients attack and destroy their own pancreatic cells. In order to systematically investigate the potential autoreactive T cell receptors (TCRs), we used a high-throughput immune repertoire sequencing tech...
Main Authors: | Yin Tong, Zhoufang Li, Hua Zhang, Ligang Xia, Meng Zhang, Ying Xu, Zhanhui Wang, Michael W. Deem, Xiaojuan Sun, Jiankui He |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-12-01
|
Series: | Genomics, Proteomics & Bioinformatics |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S167202291630184X |
Similar Items
-
Profiling of T cell repertoire in peripheral blood of patients from type 2 diabetes with complication
by: YongHui Yin, et al.
Published: (2024-01-01) -
Whole-Exome Sequencing and Analysis of the T Cell Receptor β and γ Repertoires in Rheumatoid Arthritis
by: Jooyoung Cho, et al.
Published: (2024-03-01) -
Perturbations in the T cell receptor β repertoire during malaria infection in children: A preliminary study
by: Augustina Frimpong, et al.
Published: (2022-10-01) -
Antibody repertoire sequencing analysis
by: Zhang Senxin, et al.
Published: (2022-06-01) -
Reduced diversity of intestinal T-cell receptor repertoire in patients with Crohn’s disease
by: Sung Noh Hong, et al.
Published: (2022-08-01)