Chimeric Peptidoglycan Hydrolases Kill Staphylococcal Mastitis Isolates in Raw Milk and within Bovine Mammary Gland Epithelial Cells
<i>Staphylococcus aureus</i> is a major causative agent of bovine mastitis, a disease considered one of the most economically devastating in the dairy sector. Considering the increasing prevalence of antibiotic-resistant strains, novel therapeutic approaches efficiently targeting extra-...
Main Authors: | Anja P. Keller, Shera Ly, Steven Daetwyler, Fritz Eichenseher, Martin J. Loessner, Mathias Schmelcher |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-12-01
|
Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/14/12/2801 |
Similar Items
-
MEndoB, a chimeric lysin featuring a novel domain architecture and superior activity for the treatment of staphylococcal infections
by: Christian Roehrig, et al.
Published: (2024-02-01) -
Identification of key peptidoglycan hydrolases for morphogenesis, autolysis, and peptidoglycan composition of <it>Lactobacillus plantarum</it> WCFS1
by: Rolain Thomas, et al.
Published: (2012-10-01) -
Functional profiling of CHAP domain-containing peptidoglycan hydrolases of Staphylococcus aureus USA300 uncovers potential targets for anti-staphylococcal therapies
by: Min Wang, et al.
Published: (2024-09-01) -
The Molecular Basis for <i>Escherichia coli</i> O157:H7 Phage FAHEc1 Endolysin Function and Protein Engineering to Increase Thermal Stability
by: Michael J. Love, et al.
Published: (2021-06-01) -
Systemic application of bone-targeting peptidoglycan hydrolases as a novel treatment approach for staphylococcal bone infection
by: Anja P. Keller, et al.
Published: (2023-10-01)