Sex differences in the human metabolome

Highlights Metabolomics is the gold-standard analytical approach to detect metabolic signatures in human biofluids. Analyzing the metabolome at the baseline in healthy individuals is important to identify metabolite signatures to be attributed to one sex or both. Differences in the metabolome of bio...

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Bibliographic Details
Main Authors: Michele Costanzo, Marianna Caterino, Giovanni Sotgiu, Margherita Ruoppolo, Flavia Franconi, Ilaria Campesi
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Biology of Sex Differences
Subjects:
Online Access:https://doi.org/10.1186/s13293-022-00440-4
Description
Summary:Highlights Metabolomics is the gold-standard analytical approach to detect metabolic signatures in human biofluids. Analyzing the metabolome at the baseline in healthy individuals is important to identify metabolite signatures to be attributed to one sex or both. Differences in the metabolome of biofluids are sex- and age-dependent. Sex is not still adequately considered in metabolomics-based investigations.
ISSN:2042-6410