Mapping splice QTLs reveals distinct transcriptional and post-transcriptional regulatory variation of gene expression and identifies putative alternative splicing variation mediating complex trait variation in pigs

Mapping splice QTLs reveals distinct transcriptional and post-transcriptional regulatory variation of gene expression and identifies putative alternative splicing variation mediating complex trait variation in pigs

Abstract Background Alternative splicing is an important step in gene expression, generating multiple isoforms for the same genes and greatly expanding the diversity of proteomes. Genetic variation in alternative splicing contributes to phenotypic diversity in natural populations. However, the genet...

Full description

Bibliographic Details
Main Authors: Fei Zhang, Deborah Velez-Irizarry, Catherine W. Ernst, Wen Huang
Format: Article
Language:English
Published: BMC 2023-05-01
Series:BMC Genomics
Subjects:
Splice QTL
Expression QTL
Regulatory variation of gene expression
Pigs
Online Access:https://doi.org/10.1186/s12864-023-09314-4

Internet

https://doi.org/10.1186/s12864-023-09314-4

Similar Items