cis-Acting elements and trans-acting factors in the transcriptional regulation of raf kinase inhibitory protein expression.

cis-Acting elements and trans-acting factors in the transcriptional regulation of raf kinase inhibitory protein expression.

The Raf kinase inhibitory protein (RKIP) is down-regulated in multiple types of human cancers. Decreased RKIP transcription activity may be one of the major mechanisms responsible for the downregulation of RKIP expression in human diseases. To test this hypothesis, we need to gain basic knowledge of...

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Bibliographic Details
Main Authors: Boyan Zhang, Ou Wang, Jingchao Qin, Shuaishuai Liu, Sheng Sun, Huitu Liu, Jian Kuang, Guohua Jiang, Wei Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3873293?pdf=render

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