Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease

Dickkopf-1 Acts as a Profibrotic Mediator in Progressive Chronic Kidney Disease

Chronic kidney disease (CKD) is a serious public health problem. Due to a high variability in the speed of CKD progression to end-stage renal disease (ESRD) and the critical involvement of Wnt/β-catenin signaling in CKD, we investigated the role of the Wnt antagonist Dickkopf-1 (DKK1) in CKD progres...

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Bibliographic Details
Main Authors: Yung-Chien Hsu, Cheng-Chih Chang, Ching-Chuan Hsieh, Yu-Ting Huang, Ya-Hsueh Shih, Hsiu-Ching Chang, Pey-Jium Chang, Chun-Liang Lin
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
CKD
end-stage renal disease
DKK1
β-catenin
renal fibrosis
Online Access:https://www.mdpi.com/1422-0067/24/8/7679

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