Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature
Jorge Lobo's disease is a chronic granulomatous cutaneous-subcutaneous mycosis caused by the fungus Lacazia loboi, seen mainly in tropical and subtropical regions. Malignant transformation rarely occurs in this infection. In the present manuscript, we report two cases of Jorge Lobo's disea...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Medical Mycology Case Reports |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211753922000161 |
| _version_ | 1817999283049201664 |
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| author | Arival Cardoso de Brito |
| author_facet | Arival Cardoso de Brito |
| author_sort | Arival Cardoso de Brito |
| collection | DOAJ |
| description | Jorge Lobo's disease is a chronic granulomatous cutaneous-subcutaneous mycosis caused by the fungus Lacazia loboi, seen mainly in tropical and subtropical regions. Malignant transformation rarely occurs in this infection. In the present manuscript, we report two cases of Jorge Lobo's disease complicated by invasive squamous cell carcinoma: a 67-year-old man with a 26 -year history of Jorge Lobo's disease. In this case, the malignant tumor was surgically removed. The second case was a 75-year-old man with 22-year history of mycosis. In both patients the diagnosis of squamous cell carcinoma was confirmed by histopathological examination. There was no an immunocompromised state associated in these patients. The cases, diagnosis, complication, histopathologic findings of this disease are discussed. |
| first_indexed | 2024-04-14T03:06:37Z |
| format | Article |
| id | doaj.art-f3588843a1f946d9926a3e68f14d802a |
| institution | Directory Open Access Journal |
| issn | 2211-7539 |
| language | English |
| last_indexed | 2024-04-14T03:06:37Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Medical Mycology Case Reports |
| spelling | doaj.art-f3588843a1f946d9926a3e68f14d802a2022-12-22T02:15:43ZengElsevierMedical Mycology Case Reports2211-75392022-09-01371316Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literatureArival Cardoso de Brito0Service of Dermatology, Department of Dermatopathology, Federal University of Para (UFPA), Av. Generalíssimo Deodoro, 805 APT-302, CEP: 66050-160, Nazaré, Belem, Para, BrazilJorge Lobo's disease is a chronic granulomatous cutaneous-subcutaneous mycosis caused by the fungus Lacazia loboi, seen mainly in tropical and subtropical regions. Malignant transformation rarely occurs in this infection. In the present manuscript, we report two cases of Jorge Lobo's disease complicated by invasive squamous cell carcinoma: a 67-year-old man with a 26 -year history of Jorge Lobo's disease. In this case, the malignant tumor was surgically removed. The second case was a 75-year-old man with 22-year history of mycosis. In both patients the diagnosis of squamous cell carcinoma was confirmed by histopathological examination. There was no an immunocompromised state associated in these patients. The cases, diagnosis, complication, histopathologic findings of this disease are discussed.http://www.sciencedirect.com/science/article/pii/S2211753922000161 |
| spellingShingle | Arival Cardoso de Brito Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature Medical Mycology Case Reports |
| title | Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature |
| title_full | Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature |
| title_fullStr | Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature |
| title_full_unstemmed | Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature |
| title_short | Invasive squamous-cell carcinoma in Jorge Lobo's disease: Report of two cases and review of the literature |
| title_sort | invasive squamous cell carcinoma in jorge lobo s disease report of two cases and review of the literature |
| url | http://www.sciencedirect.com/science/article/pii/S2211753922000161 |
| work_keys_str_mv | AT arivalcardosodebrito invasivesquamouscellcarcinomainjorgelobosdiseasereportoftwocasesandreviewoftheliterature |