Integrated modeling framework reveals co-regulation of transcription factors, miRNAs and lncRNAs on cardiac developmental dynamics

Integrated modeling framework reveals co-regulation of transcription factors, miRNAs and lncRNAs on cardiac developmental dynamics

Abstract Aims Dissecting complex interactions among transcription factors (TFs), microRNAs (miRNAs) and long noncoding RNAs (lncRNAs) are central for understanding heart development and function. Although computational approaches and platforms have been described to infer relationships among regulat...

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Bibliographic Details
Main Authors: Shumin Li, Bin Yan, Binbin Wu, Junhao Su, Jianliang Lu, Tak-Wah Lam, Kenneth R. Boheler, Ellen Ngar-Yun Poon, Ruibang Luo
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Stem Cell Research & Therapy
Subjects:
Data integration
Cardiac development and function
Transcription factors
miRNAs
lncRNAs
Gene regulatory network
Online Access:https://doi.org/10.1186/s13287-023-03442-0

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