Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review
Introduction: Plasma cell myeloma is the distortion of differentiated B lymphocytes which is associated with uncontrolled proliferation of plasma cells in bone marrow. Some studies propound a role for HHV-8 virus in pathogenesis of plasma cell myeloma. Yet the findings are inconsistent. In this arti...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2018-09-01
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| Series: | Reviews in Clinical Medicine |
| Subjects: | |
| Online Access: | https://rcm.mums.ac.ir/article_11668_6946da6be5614e96c479f95d50d2efb6.pdf |
| _version_ | 1797976109831159808 |
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| author | Mohammad Hadi Sadeghian Zahra Rezaei Dezaki Seyyede Fatemeh Shams Sepideh Shakeri |
| author_facet | Mohammad Hadi Sadeghian Zahra Rezaei Dezaki Seyyede Fatemeh Shams Sepideh Shakeri |
| author_sort | Mohammad Hadi Sadeghian |
| collection | DOAJ |
| description | Introduction: Plasma cell myeloma is the distortion of differentiated B lymphocytes which is associated with uncontrolled proliferation of plasma cells in bone marrow. Some studies propound a role for HHV-8 virus in pathogenesis of plasma cell myeloma. Yet the findings are inconsistent. In this article we reviewed the literatures to determine the HHV-8 virus role in plasma cell myeloma pathogenesis.Methods: In this systematic review, scientific databanks including PubMed, Scopus, Embase, ISI, and Google scholar were searched. The search was based on the subsequent keywords and medical terms in title; different combinations of keywords were used, they were compatible with MeSH terms.Result: Four articles declared that there is no link between the HHV-8 and the pathogenesis of plasma cell myeloma; while five reported a connection between the virus and myeloma, arguing that virus infection will lead to disease progression.Conclusion: There are differences between the results of the studies. It is required to do further researches about the association of HHV-8 and plasma cell myeloma. |
| first_indexed | 2024-04-11T04:46:09Z |
| format | Article |
| id | doaj.art-f35fac555c0c4e49b4313c8418900ef0 |
| institution | Directory Open Access Journal |
| issn | 2345-6256 2345-6892 |
| language | English |
| last_indexed | 2024-04-11T04:46:09Z |
| publishDate | 2018-09-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Reviews in Clinical Medicine |
| spelling | doaj.art-f35fac555c0c4e49b4313c8418900ef02022-12-27T13:07:20ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922018-09-01539510010.22038/rcm.2018.32149.123511668Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic ReviewMohammad Hadi Sadeghian0Zahra Rezaei Dezaki1Seyyede Fatemeh Shams2Sepideh Shakeri3Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Cancer Molecular Pathology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.Introduction: Plasma cell myeloma is the distortion of differentiated B lymphocytes which is associated with uncontrolled proliferation of plasma cells in bone marrow. Some studies propound a role for HHV-8 virus in pathogenesis of plasma cell myeloma. Yet the findings are inconsistent. In this article we reviewed the literatures to determine the HHV-8 virus role in plasma cell myeloma pathogenesis.Methods: In this systematic review, scientific databanks including PubMed, Scopus, Embase, ISI, and Google scholar were searched. The search was based on the subsequent keywords and medical terms in title; different combinations of keywords were used, they were compatible with MeSH terms.Result: Four articles declared that there is no link between the HHV-8 and the pathogenesis of plasma cell myeloma; while five reported a connection between the virus and myeloma, arguing that virus infection will lead to disease progression.Conclusion: There are differences between the results of the studies. It is required to do further researches about the association of HHV-8 and plasma cell myeloma.https://rcm.mums.ac.ir/article_11668_6946da6be5614e96c479f95d50d2efb6.pdfetiologyhuman herpes virus 8multiple myeloma |
| spellingShingle | Mohammad Hadi Sadeghian Zahra Rezaei Dezaki Seyyede Fatemeh Shams Sepideh Shakeri Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review Reviews in Clinical Medicine etiology human herpes virus 8 multiple myeloma |
| title | Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review |
| title_full | Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review |
| title_fullStr | Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review |
| title_full_unstemmed | Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review |
| title_short | Correlation between Human Herpes virus 8 (HHV8-) and Plasma Cell Myeloma: a Systematic Review |
| title_sort | correlation between human herpes virus 8 hhv8 and plasma cell myeloma a systematic review |
| topic | etiology human herpes virus 8 multiple myeloma |
| url | https://rcm.mums.ac.ir/article_11668_6946da6be5614e96c479f95d50d2efb6.pdf |
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